Let’s double the NIH budget! New treatments and cures for dread diseases! Let’s go! Who hates cancer? Who hates diabetes? Who hates strokes? I know I do and I bet you do too. Let’s make it a priority today and gift ourselves with better health tomorrow.

With Katerina Rohlenova pleased to announce the 2026 Prague Metabolism and Signaling Meeting (June 24-27). Two Keynotes (Vousden & Hall) and 30+ speakers in metabolism, mitochondria, aging, mTOR, & more. Please RT. Info, registration, & student discounts at: praguemetabolismsymposium.com

NIH announces end to funding for animal-only studies drugdiscoverytrends.com/nih-announces-…

📰New paper from the lab! Using our transgenic TCR model we reveal that T cell beta-selection can be bypassed via a γδ TCR alternative path that allows T cell maturation to continue. This path appears highly dependent on IL-7 signaling. Read here! academic.oup.com/immunohorizons…

Stronger legs are associated with larger brain volume & slower cognitive decline. 🧵1/7

1/ Many genomics mistakes are hard to catch in the code. They’re in the data you never looked at. Genome browsers can change that. Here’s how.

The NIH has decided that scientists can only submit 6 grants a year. OK. But you need a score that’s < 10% at least to get funded. Meaning, at best, 1 out of 10 grants you submit will have a chance (YMMV of course). 🫠

SCGE researchers develop a base editing approach exploiting a naturally occurring CD33 single nucleotide polymorphism leading to removal of full-length CD33 surface expression on edited cells. #PublicationFriday nature.com/articles/s4146…

Longevity gene therapy paper retracted. First retraction for George Church. Situation involved BioViva, co. headed by unlikely longevity figure Liz Parrish. Best quote from co-author: “I have retired and I am in Greenland. I do not have to talk to you.” retractionwatch.com/2025/08/13/geo…

Huge 3D Printing Breakthrough! Caltech is printing metal atom by atom. A hydrogel scaffold soaked in metal salts becomes the blueprint, the gel burns away, and oxygen is stripped in a hydrogen-rich chamber, leaving alloys crafted with surgical precision. They can change metal

Even as we approach 3 years without Chris, we often find ourselves reminiscing on memories with him. His family asked us to share an invitation to his upcoming memorial on October 12. If you would like to attend, please RSVP using this form: forms.gle/ztYSxgTgDBn75j…

SCGE researchers demonstrate proof-of-concept of multiorgan mutation correction in cystic fibrosis using peptide nucleic acids encapsulated in polymeric nanoparticles and delivered systemically in utero. #PublicationFriday pnas.org/doi/10.1073/pn…

Following injury from a heart attack, immune cells called neutrophils release a peptide that punctures stressed heart cells and destabilizes their electrical activity. This triggers life-threatening arrhythmias. These findings in Science offer a novel explanation—and potential

Now online! IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity dlvr.it/TN04V7

Huge thanks to the Minneapolis City Soccer Club! This year’s Gene Party raised $7,500 for the UMN Center for Genome Engineering! 🧬⚽️ Minneapolis City SC Center for Genome Engineering

Targets of protective immunity and opportunities in hepatitis C virus vaccine development bit.ly/3VgYyeL

This protein could be used to sense magnetic fields and temperatures inside individual cells. sciencenews.org/article/biolog…