New The CAN-BIND Depression Network data hot off the press! Authors found that CYP2C19 rs4244285 was associated with weight gain in IM and NMs but not PMs, suggesting a biomarker and functional target for understanding antidepressant weight gain. thieme-connect.de/products/ejour…

Highlight of the day? Running into Tarek K. Rajji while shopping on Bloor Street and testing dress shirts together - on sale! 😄 #bargain #winwin

Grateful for this CIHR Award to study genomic/pharmacogenomic factors contributing risk for difficult-to-treat (or treatment-resistant) major depressive disorder (MDD). Study participants CAMH with MDD will obtain evidence-based, state-of-the-art pharmacogenetic

🚨Open #postdoc position! Join me and Johan Lundberg @lundberglab.bsky.social at Karolinska Institutet @StratNeuro on a exciting collaborative project to study the molecular mechanisms behind the antidepressant effects of psychedelic compounds. Apply here: ki.varbi.com/what:job/jobID… Please RT 🙌

#Pharmacogenetic Variants and Plasma Concentrations of Antiseizure Drugs "#CYP2C9 and #CYP2C19 genotypes encoding low enzymatic capacity were associated with a clinically relevant increase in #phenytoin plasma concentrations" jamanetwork.com/journals/jaman…

Daniel J. Mueller 🧠🔬 kicking off the CCNP #CCNP2024 meeting in Calgary! An exciting program bringing together the best of basic, translational and clinical neuropsychopharmacology research in Canada!

Dr. Isabelle Boileau from CAMH, keynote speaker at #CCNP2024, presenting" Beyond dopamine: PET imaging discoveries in Addiction Neuroscience" - brilliant talk! For more conference details, see ccnp.ca

Ready for my #WCPG2024 poster on the AMBER project on causal mechanisms for antidepressants. We are running #pharmacogenomic GWAS studies for antidepressant response. Have studies? Have ideas? Talk to me 1/2

Inauguration of the first "Pharmacogenomics Interest Group (PIG)" meeting at the #WCPG2024 Many attendants joined; great to see so much interest in translational research, aimed to improve treatment for the individual patient. Main goals of the "PIG": - Networking to promote

Coming up next - A practical guideline on pharmacogenetics unser consideration of population diversities: #WCP24

#ACNP2024 - As usual, great science, inspiration, networking, and friendship!

Do plasma levels of psychotropic medications (plus their metabolites) matter for response and side effects? Yes, they do. Do pharmacogenetic (PGx) tests of CYP enzymes allow to predict plasma levels/metabolites? Yes, they do. Do PGx tests allow to predict (and explain past)

The Royal Ottawa Mental Health Centre welcomes Dr. Benoit Mulsant as the incoming chief of staff. A leader in psychiatry and digital health, he brings decades of experience to guide The Royal’s strategic transformation. theroyal.ca/news/dr-benoit…

This meta-analysis by Lauri Tuominen, Synthia Guimon et al. found widespread reductions in muscarinic and nicotinic receptors in schizophrenia, confirmed by neuroimaging and post-mortem studies. nature.com/articles/s4138…