(11/12) Our preprint shows how a death domain signaling complex is not solely controlled by oligomerization but can integrate a phosphorylation regulatory switch to control signal transduction. This mechanism can be targeted with small molecule inhibitors like Zimlovisertib.

Great work from the @mtaylor_berlin lab! Check out their new #preprint "IRAK4 autophosphorylation controls inflammatory signaling by activating IRAK oligomerization". For a first overview of the preprint, you can read this awesome thread by first author Niranjan Anirudh Srikanth 👇

Gegen den Rechtsdrift: Wir brauchen eine offene Gesellschaft! Mein Beitrag heute Frankfurter Allgemeine faz.net/1.9452332?prem…

Great new preprint from our friends Max Planck Institute for Infection Biology Marcus Taylor IRAK4 autophosphorylation controls inflammatory signaling by activating IRAK oligomerization biorxiv.org/content/10.110…

You need a proteins, but a few only and delivered in a non-invasive manner? For single molecule imaging maybe? Or to reconstitute functioning a knockout? Purba Kashyap has the solution! So excited to see it out. Constructs soon on Addgene nature.com/articles/s4159…

Now on Freie Universität website, Purba Kashyap s new paper: fu-berlin.de/en/presse/info…

This was a lot of fun! Thank you, Ewerslab and Purba Kashyap, for getting us involved. I'm excited to see how the community uses these powerful tools! Our small contribution was spearheaded by the amazing Niranjan Anirudh Srikanth and Fakun Cao

📢 Voices in Infection Biology Join us for a seminar with Michael Dustin from Kennedy Institute of Rheumatology, kindly hosted by Marcus Taylor. 🗓️ Wednesday, March 20 🕓 4 pm CET (Berlin time) Registration and abstract: mpiib-berlin.mpg.de/events/37163/2…

📢 Voices in Infection Biology Join us next Wednesday for Julia Mahamid's (EMBL) talk "Enabling discovery by in-cell structural biology", kindly hosted by Simone Reber. 🗓️ Wednesday, April 24 🕓 4 pm CET (Berlin time) Registration and abstract: mpiib-berlin.mpg.de/events/37238/2…

Do you plan to attend American Society for Cell Biology this year? Do you work in the field of immune cell biology? If yes, then we have a special interest subgroup just for you! 1/3

Meghan Morrissey , Marcus Taylor, and I are organizing a subgroup called “Immune cell biology: from physical biology to pharmaceutical application”. We will feature talks that range from fundamental basic science to translational application in the field of immune cell biology. 2/3

If you’d like to be considered for this subgroup, please submit your abstract by August 6. Looking forward to seeing your cool science! ascb.org/cellbio2024/ab… 3/3

Just a reminder that American Society for Cell Biology abstract submission deadlines are creeping up (Aug 6)! Please considering submitting an abstract to our subgroup on immune cell biology! ascb.org/cellbio2024/ab… Meghan Morrissey Marcus Taylor

Super happy this is online! Tobias Kletter shows how cytoplasmic material properties control spindle architecture and scaling! 🤩 Thanks to the fantastic team Abin Biswas, Sebastian Reusch, Omar Munoz & Vasily Zaburdaev 🇺🇦 #ALMF EMBL 🙌 biorxiv.org/content/10.110…

So excited and grateful for this fantastic support for our lab! This is an honor earned by the lab as a community of fantastic, smart, and wonderful colleagues. Congrats, team!

Britain's prosperity depends on its universities -- but they have been perilously neglected. Wellcome letter in The Times and The Sunday Times today ✍️🏻

Our 🐸 have finally moved Max Planck Institute for Infection Biology! We will welcome them with a talk by Sabine Sabine Petry 🎇 Join us Aug, 21st

This Wednesday, Sabine Sabine Petry will talk about "Building the microtubule cytoskeleton via microtubule nucleation" Max Planck Institute for Infection Biology! Come for the science, stay for the frog welcome party 🐸