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Next up is Andreas E. Moor talking about cancer organoids and drug development. They are profiling cancer heterogeneity driven aberrant signaling and interactions in primary cancer tissue and colon cancer #organoids using spatial transcriptomics D-BSSE, ETH Zurich

BaCell3D D-BSSE, ETH Zurich Thanks Ashley Maynard and organizers for the invitation! Such an inspiring day so far, loving this conference , the people and the venue.

Soooo happy to share the results of my PhD project in the MoorLab! The seed and soil hypothesis postulates that metastases will only grow in favorable environments. Here we forget about the seed and focus on the soil. Which factors in the liver promote or suppress seeding? 🧵👇

Super excited about this new preprint of the lab 🚀🚀. Congrats to Costanza Borrelli and all coauthors. Our research delves into the world of tumor-hepatocyte interactions, spotlighting #PlexinB2 as a key player in regulating liver metastasis.

Very innovative approach, cool results, excellent science with important putative implications - simply a pleasure to read. Congratulations !!

Excited to give a talk about our recent work from the sendoel-lab at #KSSingleCell23 Keystone Symposia tomorrow. "Tissue-wide Single-cell CRISPR Uncovers Distinct TNFa Modes in Clonal Expansion and Transformation in the Skin". In collaboration with MoorLab and Stephanie Ellis

MoorLab moved to the new D-BSSE, ETH Zurich building from today :)! looking forward to interacting with Biozentrum, University of Basel more 👩‍🔬👨‍🔬

Check out the three open positions for Assistant Professors TT at our department in Basel > bsse.ethz.ch/department/ope… Please share! ETH Zurich #Biomedicine #Biodata #Genomics #Bioengineering #jobopportunity

Great work by @handlerkristina !

ISCHIA is online at Mol Syst Biol! So much fun to work with the one and only Ati! Takeaway message from this project: lab retreats are fun and inspirational, even if no scientific activity is planned! Keep it up MoorLab! embopress.org/doi/full/10.10…

ISCHIA uses the inherent proximity of #spatialtranscriptomics spot data to reconstruct co-occurring cell-type networks. Application to ulcerative colitis patient data reveals #inflammation-induced cellular networks ➡️ embopress.org/doi/full/10.10… Andreas E. Moor MoorLab D-BSSE, ETH Zurich

Well, this is what happens when two scientists become best friends (Costanza Borrelli) and go on a relaxing retreat to a beautiful island in gulf of Naples with delicious mozzarella and wine... They make science! embopress.org/doi/full/10.10…

Congrats Costanza Borrelli and Alessandra Gurtner👏 Arnold_lab 🥂

Clonal expansions can remodel entire tissues even when they appear normal, but what mechanisms drive this? And how do these processes differ from tumorigenesis? Out nature, we identify distinct TNF programs during tumor evolution. 🧵 nature.com/articles/s4158…

Next week check in again, same space, same time: more in vivo screening to come from the MoorLab ☺️🚀

Researchers at ETH Zurich have uncovered how #Colorectal #CancerCell's colonise the liver. Their findings could open up new ways to suppress this process in the future. brnw.ch/21wLtkS D-BSSE, ETH Zurich

My PhD work in the MoorLab is out 🥳🤩🤪 Five year after that lunch break discussion with Andreas E. Moor! Thanks Andreas for believing in our crazy outside-in screen and to ALL the people that helped along the way!