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Happy to see our collaborative paper with Cyrus Vaziri’s lab demonstrating that RNF168 is recruited to damaged replication forks via a degenerative PIP box and its MIU1 ubiquitin binding domain is finally out in Nucleic Acids Res : academic.oup.com/nar/advance-ar…

Molecular mechanism of parental H3/H4 recycling at a replication fork nature.com/articles/s4146…

Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β biorxiv.org/content/10.110…

Happy to share our new publications in Nucleic Acids Research on the regulation of PRIMPOL doi.org/10.1093/nar/gk… doi.org/10.1093/nar/gk…

Thanks to the RepliFate symposium at The Netherlands Cancer Institute we had a great opportunity to engage with the Dutch scientific community 👏

The Danish Bioimaging Network is hosting Professor Lothar Schermelleh for a talk on December 10th at 9 am. Sign up here: eventsignup.ku.dk/talkbylotharsc…

Check out latest from the Walter-Pellman collaboration, revealing how the replisome is remodeled in mitosis to allow CMG eviction, which we propose minimizes fallout from under-replication. biorxiv.org/content/10.110…

Join us this Tuesday at 4 pm for the next EDRA (European DNA Repair Alliance) Martijn S Luijsterbug Martijn Luijsterburg will delve into how STK19 facilitates the clearangr of lesion-stalled RNAPII during transcription-coupled DNA repair

Maria-Elena Torres-Padilla Awarded the Leibniz-Preis 2025 🎉 👏 The German Research Foundation (#DFG) recognizes the outstanding research of Prof. Maria-Elena Torres-Padilla with Germany’s most prestigious scientific award: the Gottfried Wilhelm #LeibnizPreis.

In our latest preprint we analyzed how abasic (AP) sites affect DNA replication: - AP sites stall DNA synthesis ⛓️‍💥 - Leading APs stall replisomes but lagging APs don’t 🛑/✅ - TLS is crucial for bypass of both leading and lagging strand AP sites 🛠️🧬 biorxiv.org/content/10.110…

Thrilled to share our latest work in nature! We show how cancer cells navigate DNA replication despite DNA damage, revealing new insights into genome stability. Huge thanks to my incredible collaborators! Check it out here: nature.com/articles/s4158…

🎨 🔬 Science Meets Art This week, we are excited to welcome @Pei-Ying Lin to the Duxin lab at the @Biotech Research & Innovation Centre (BRIC), University of Copenhagen as part of the RepliFate Artists in Residence program. Pei will spend two days immersed in our lab routine.

Natasha biotech Her goal? To observe, learn, and draw inspiration from the molecular world we study, translating the complexities of DNA replication into artistic expression. #SciArt

🚀 We just launched the brand-new #KinaseLibrary website, directly connected to the recently released Python package! Explore kinase-substrate relationships, run enrichment analyses, and visualize phosphoproteomics data—no coding required! kinase-library.phosphosite.org The Kinase Library

If you’d like to gain hands-on training in the basics of mass spectrometry and proteomics bioinformatics, then this course is for you! Make sure you’ve submitted your application by 6 April: ebi.ac.uk/training/event… This course is organised in association with VIB

Thrilled to share our latest work at Science Advances. Great collab with Costanzo, Masson, Freire and Reyes labs. HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances science.org/doi/10.1126/sc…

Let's begin the amazing 2025 Spring Season of GIIN Seminars! Join us on Tuesday, April 1st from 5-6 PM (Rome Time) for a lively discussion with Marta Kovatcheva and Mate Maus Click here to join: uniroma1.zoom.us/j/95149984403

It’s time for new duo: Julius & his PI Lorenza Lorenza Penengo Lab from the University of Zurich. They study the ISG15 system in DNA rep—but there’s more! One could be found scaling alpine peaks, while the other might just trade the lab for the thrill of mushroom hunting. Curious to know more? 🍄

🔬 New from the Farnung Lab: We have established a fully in vitro reconstituted chromatin replication system and we report the first cryo-EM snapshots of the human replisome engaging nucleosomes. 🧬✨tinyurl.com/replisome

A new protein sequencing method, which uses a biological motor to pull a protein through a tiny nanopore, could revolutionise protein analysis. chemistryworld.com/news/nanopore-…