New preprint! 🚨Keck Medicine of USC Institute for Regenerative Medicine We started with the simple question: What happens when we transplant stem cells into a mouse model of #stroke, and what are the interactions between graft and host? Took us only 5 yrs to find out😀: biorxiv.org/content/10.110… 1/10 🧵

We present a major leap forward in large-scale transcranial fluorescence imaging of brain dynamics ! Kudos to Zhenyue Chen, Quanyu Zhou, Chaim Glück and the whole team 🎊 Another terrific collaboration with Mohamad Amki, Susanne Wegener nature.com/articles/s4146…

New cover for Neuron! 🧠 Big Role of Tiny Blood Vessels🩸 Tiny vessels connecting arteries together can rescue brain after stroke! Mohamad Amki and @susewegener found out that in stroke patients and mice, these tiny vessels (collaterals) regulate reperfusion after stroke.

Our highlight of a great new paper from ⁦⁦Mohamad Amki⁩ ⁦Susanne Wegener⁩ lab. Collaterals and stroke reperfusion: Too few leads to too much: Neuron cell.com/neuron/abstrac…

Did you know that if you ablate astrocytes, perlesional astrocytes divide and give birth to daughter astrocytes? A very exciting discovery from great colleagues. Kudos to Matthias Wyss Bruno Weber Lab et al., #astrocytes #progenitors Institute of Pharmacology and Toxicology Universität Zürich

New lab preprint for those interested in #Angiogenesis and #notch signalling in the mature (healthy) mouse cortex. Congrats to the team, especially Ale and Ben for leading the work. biorxiv.org/content/10.110…

Can stem cells repair the stroke-injured brain? And what are the underlying mechanisms? We talk about evidence for direct cell replacement, release of supportive factors, safety, immune evasion, graft-host interactions and more! Published in Brain academic.oup.com/brain/advance-…

Happy to share our new paper published in PNASNews. growkudos.com/publications/1… via @growkudos I am incredibly grateful to all co-authors and contributors Bruno Weber Lab Daniel Razansky Susanne Wegener Institute of Pharmacology and Toxicology Unispital_USZ

Please, RT If you love #macrophages #neutrophils #dendriticcells don't miss #phagocyte2025 📆26-28 March 2025 📍CNIC Madrid 🌍top speakers phagocytes2025.com/index.php/spea… 🔬Submit your latest research for oral presentation or poster phagocytes2025.com/index.php/abst…

That was one of the best meetings I ever had! Thank you Anna Devor Goyo Sevillano Mark Nelson Lab and all colleagues for the great discussions. I was honored by your invitation.

📆ny resolution REGISTER NOW in #phagocytes25 phagocytes2025.com 20 🔝speakers 28 short talks + posters 🌍Madrid CNIC 📆26-28 March '25 Organized by SEInmunología Support by CRC TRR332 PILOT_TRR359 Inmunotek EMBO Events Bursaries by EFIS European Journal of Immunology

So great to see our cover on the new Immunity issue! Kudos to the artistic touch of Alessandro Matera ☺️ with Compagnion Anne-Claire and the many collaborators! read more about microglia and Inpp5d (SHIP1) in brain development

🧠 Our new study in Cephalalgia (journals.sagepub.com/doi/full/10.11…) explores genetic variants in FHM1-3 genes using UK Biobank data. A genotype-first approach revealed that these 🧬variants ⬆️#migraine risk—and surprisingly, a link to ⬇️ #epilepsy was discovered. Here’s what we found🧵

Interleukin-34-dependent perivascular macrophages promote vascular function in the brain: cell.com/immunity/fullt… Immunity

Excited to share our new study showing that perivascular macrophages promote vascular function in the brain. A greater collaboration with the great Melanie Greter. Huge congratulations to everyone involved! University of Zurich Immunity

Astrocytic GLUT1 deletion in adult mice enhances glucose metabolism and resilience to stroke nature.com/articles/s4146…

You knock out #GLUT1 to impair astrocytic glucose uptake - only to find out that #astrocytes ramp up glycolysis and keep going. Metabolically resilient, and even neuroprotective. Our study in Nature Communications: nature.com/articles/s4146…