This week on Possible, we sit down with Nobel Prize Winner and Google DeepMind CEO Demis Hassabis to discuss his predictions on the next “move 37”, protein folding, and why AI will be the “most transformative technology ever.”

New Anthropic research: AI values in the wild. We want AI models to have well-aligned values. But how do we know what values they’re expressing in real-life conversations? We studied hundreds of thousands of anonymized conversations to find out.

Sam Rodriques Check out our platform at platform.futurehouse.org, and read more at our blog post below! futurehouse.org/research-annou…

Pre-order the official NotebookLM app, coming May 20th on iOS and Android! apps.apple.com/us/app/noteboo…

Today Google Research introduces a system using Gemini models designed for high fidelity text simplification, that enhances clarity while preserving meaning, detail, & nuance — and it’s available in a new feature in the Google app for iOS, Simplify. More →goo.gle/4iM6oGn

>700K people die each year due to S. aureus infection. Today we show that our AI designed new molecule, synthecin, stops drug-resistant S. aureus MRSA in mouse model💊 We created synthecin w/ SyntheMol-RL, our new RL generative AI. All open source biorxiv.org/content/10.110…

ChatGPT now can analyze, manipulate, and visualize molecules and chemical information via the RDKit library. Useful for scientific work across health, biology, and chemistry.

🚨 NEW: We made Claude, Gemini, o3 battle each other for world domination. We taught them Diplomacy—the strategy game where winning requires alliances, negotiation, and betrayal. Here's what happened: DeepSeek turned warmongering tyrant. Claude couldn't lie—everyone

The google oracle has spoken.

Claude is now being listed as an author on arXiv papers A response paper to Apple's "Illusion of Thinking" work just dropped with Claude Opus as first author, critiquing their experimental design and arguing the reasoning collapse was actually just token limit constraints.

👀Using an autonomous agent based on o3-mini and GPT-4.1, a team from Harvard, MIT & other institutions reproduced and updated an entire issue of Cochrane Reviews in two days… saving 12 person-years of work! The AI reviews captured more papers & were more accurate than humans.

Introducing your arXiv Research Agent A personal research assistant with access to arXiv + bioRxiv + medRxiv + Semantic Scholar. Upload drafts, conduct literature reviews, get insights across millions of papers MCP support coming soon 🚀

No signs of an end to rapid gains in AI ability at ever-decreasing costs yet I did my best to update my chart to take into account the price drop in o3 & the new models released by Google. GPT-4 was 2.25 years ago,so its worth noting the trend when considering the future of AI.

Nice - my AI startup school talk is now up! Chapters: 0:00 Imo fair to say that software is changing quite fundamentally again. LLMs are a new kind of computer, and you program them *in English*. Hence I think they are well deserving of a major version upgrade in terms of

Gemini Deep Research has gotten very good since it was upgraded to 2.5 Pro. Claude and ChatGPT tend to go a good job acting like analysts and building an argument, but Gemini is probably the best right now at synthesizing a coherent overview of a complex topic.

There is a lot more to explore in the paper. I encourage everyone to go and read it. 120+ pages. There is a lot of research in all areas of science. Applications range from code generation to autonomous design and optimization. If you are looking for inspiration or ideas to

ChatGPT o3-pro identifies a 1965 quote by I. J. Good hand-written in a mix of print and cursive on a note ripped into four strips in reverse order rotated 90° in alternating directions:

I'm constantly irritated that I don't have time to read the torrent of cool papers coming faster and faster from amazing people in relevant fields. Other scientists have the same issue and have no time to read most of my lengthy conceptual papers either. So whom are we writing

I am so glad there's finally hard evidence to prove what was obvious to anyone using o3 - it's far better at search than anything else out there. Now we have lmarena.ai search-specific rankings clearly showing o3 beating even dedicated search providers like Google or