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Jane Richardson’s protein ribbon diagrams have been so successful that it can be hard to remember that our cells are not, in fact, filled with colorful ribbons and broad arrows. quantamagazine.org/how-colorful-r…

We report many proteins not predicted by the genetic code. They are stable & abundant O( 10³ ) copies / cell. Generative mechanisms include codon-anticodon mismatches & RNA modifications. Their abundance depends on codon frequency & protein stability. biorxiv.org/content/10.110…

Booking is open for the Immunogenetics Workshop King's College, Cambridge on 8th November 2024. Book your place at materia1a.it/wp-content/upl…

NK cell reactivity decreases rapidly upon activation by tumor cells, independently of immune checkpoints Science Advances Thierry Walzer science.org/doi/10.1126/sc…

This is so good newyorker.com/culture/the-we…

📰 September marks the start of of the new RSV vaccination programme in England, Wales and Northern Ireland. Hear from our CEO Dr Doug Brown on why this is a pivotal moment in public health bit.ly/4dMmbn9

New paper out nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones? Here we studied adaptation of human immune systems to gender-affirming

Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis dlvr.it/TCyybM

Exciting work by Horowitz Lab @Icahn School of Medicine Mount Sinai and team! Congrats to all. HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer biorxiv.org/content/10.110…

My department at Oxford is hiring - Assistant/Associate professor level positions at Ludwig Cancer Nuffield Department of Medicine. Broad interests in cancer cell plasticity, epigenetics, epitranscriptomics, microenvironment but all areas considered. Check out ad here: nature.com/naturecareers/…

As promised here is a link to GitHub which should be a public page with my short lecture (39 slides) and 'outline/cheatsheet' - there is a ppt and pdf of the lecture github.com/jeffmold/Under…

'We are excited by the prospect of a vaccine that can potentially be used to prevent the multiple types of cancer.' Professor Simon Leedham Nuffield Department of Medicine discusses new funding from Science and Innovation at Cancer Research UK to develop a cancer prevention vaccine for Lynch syndrome. ⬇️ oxcode.ox.ac.uk/news/oxford-re…

Funding from Cancer Research UK to University of Oxford #oxCODE efforts to develop #lynchvax to prevent #cancer in people living with #lynchsyndrome. #vaccinenation #vaccine #cancerresearch #cancerprevention #funding #globalhealth vaccinenation.org/global-health/…

Great review of the handful of TCR-T trial successes: sciencedirect.com/science/articl…

I hate the TV "Big Bang Theory" vision of being a scientist. It isn't about being brilliant. It is about being curious and creative, having integrity for the data, and the ability to admit you were wrong and re-think. It is why resilience matters so much thegreatbritishbookshop.co.uk/products/becom…

Reactivation of EBV is a possible factor that causes MHC class II molecules to present neoself-antigens by decreasing the expression of the invariant chain and promoting self-reactive T cells in lupus Cell cell.com/cell/fulltext/…

Please consider applying! Faculty positions all levels in Biochemistry at the University of Michigan medschool.umich.edu/sites/default/…

Did you get your PhD in Sweden? Want to do your postdoc at Broad or MIT? Check out this 2y fellowship! Happy to discuss project ideas if you're interested in image-based profiling / data science! Deadline: Nov 15, 2024 kaw.wallenberg.org/en/calls/walle…

My department (MIT Biological Engineering) is hiring at the Assistant Professor level! We are looking for someone in immunology/immunotherapy/immune engineering, broadly defined. be.mit.edu/about/open-fac…

Elite controllers showed an exceptional ability to kill primary HIV-infected cells via ADCC adaptive mechanism involving a specific memory-like NK population expressing CD16, NKG2A, NKG2C, CD57 and CXCR3 JCI insight insight.jci.org/articles/view/…