🔥Telegram İfşa

Cofactors are a crucial part of the gene activation process. Yet, we still don't have a comprehensive understanding of how and why they are used by different genes. Proud to present our attempt to address this key question, now published nature.com/articles/s4158…

🧬New research alert! Check out our latest paper in Molecular Cell on how #GenomicContext modulates the activity of #enhancers!🔎authors.elsevier.com/c/1j5vE3vVUPRl… What a great team work of the @MattMaurano y Jef Boeke labs! Follow the thread🧵to find out more! #Genomics #SyntheticBiology

It's common knowledge that H3K9me3 correlates with DNA methylation. Can anyone point me to public human datasets of H3K9me3 ChIP-seq & WGBS that I can load to IGV to validate this correlation visually? Tried with K562 data from Encode, can't see any correlation.

Our tool Charm is out in @NAR_Open Genomics & Bioinformatics! Simulate Hi-C data for CNV, inversions, translocations & complex SV. academic.oup.com/nargab/article… 💻 github.com/genomech/charm #HiC #Genomics #SV #Bioinformatics #CharmTool