Could you try to formulate more precise and impactful questions in the field of life extension than these: 1. Where does the initial phase shift that triggers the aging cascade originate? 2. How can we induce and sustain stable self-regeneration in mature tissues without

Using AI to extend human life and solving the alignment problem are one and the same mission.

The battle of theories continues!

The Wall Street Journal reports that Warren Buffett has finally felt his age. Everything was fine—right up to 94. What can we say? Every member of this chat would yell: go all-in! Pour every cent into head transplants, cryonics, full-organ perfusion, warp-speed innovation. Stop

Why are there so few prizes for small but realistic achievements in life extension?

If I had the opportunity to organize a conference on how to extend human life, I would suggest not discussing the biology of aging, since there are already more than enough conferences on that topic. Instead, I would propose focusing on the following question: Which cultural

Never tire of reminding everyone that the fight against aging is important.

I keep trying to persuade Pavel Durov to fund aging research

If anybody wants to build a local cryopreservation organization, reach out to us. We'll ship you everything you need at cost and train you for free! First packages going out :)

Trump needs to go all-in on Life Extension — but of course he won’t, because that would require having a brain.

Mind Breaking Through Misha Batin, Elizaveta Povysheva 48” × 60”, acrylic on canvas. Featured in the Immortality or Death exhibition, Vitalist Bay, May 2025. At first glance, the painting depicts an ordinary San Francisco courtyard—a typical day, a familiar rhythm of life. Yet

It’s hard to imagine a simpler and more impactful action for life extension than recommending Alexander Panchin’s book, Immortality or Death, to everyone around you amazon.de/dp/B0F93JBB1D

It’s an insanely tough question: why haven’t people dropped everything to battle their own deaths? My own answer keeps changing, but it always circles back to this: we’re not really in charge of ourselves. In fact, it’s not even clear what a person “in and of themselves” is, or

Money and capital are Darwinian entities. They possess heredity, variation, and selection.

Chugai Pharmaceutical Co, with a market capitalization of $82 billion, has acquired the rights to develop an anti-aging drug from Gero. This is a huge piece of news for our entire field.

What happens if you constantly restore the damage to the brain caused by aging? You will achieve immortality