We are seeking a new PhD student to join our growing team, on a fully funded studentship at the University of Liverpool to help us develop new therapies for the rare disease Alkaptonuria. Please share! Brendan Norman University of Liverpool News @AKUSociety findaphd.com/phds/project/d…

We’re excited to share our work showing the widely used, non-toxic molecule propylene glycol prevents infection by many different human viruses including SARS-CoV-2 and influenza A virus, published today EMBO Mol. Medicine. A thread 1/3 doi.org/10.15252/emmm.…

Pleased to share a new methods paper from the lab led by Anna Gray to image and analyse the endothelial glycocalyx in the live brain with Ingo Schiessl Lydia Becker Institute WTCCMR UKProteoglycans BSMB ISMB BrainInflammationGrp sciencedirect.com/science/articl…

Join us on the 7th of Dec for a free event organised by Tony K and ourselves, with a keynote presentation by Farshid Guilak, discussing smart advances in musculoskeletal ageing research. tinyurl.com/2txs7h47. The Guilak Lab NIHR Newcastle BRC Newcastle University STEM Outreach EngageFMS@NclUni @VOICE__Global

Protein condensation regulates water availability in cells nature.com/articles/d4158…

Happy to have contributed to investigation of circadian clocks in breast cancer with Shiyang Li in Qing Jun Meng's lab funded by a collaborative Breast Cancer Now grant with Sacha Howell in Manchester Breast Centre Manchester Cancer Research Centre and Division of Cancer Sciences pnas.org/doi/epdf/10.10…

Come join our team? We have a postdoc position open. Deadline 17th March mrc.tal.net/vx/mobile-0/ap…

Another PhD Studentship from Reynard Lab - Newcastle University with NUBI_YoungLab RMSCT @ Newcastle University Cells, Genes and Molecules - Newcastle !!! Please circulate! PhD studentship in @NUBiosciences : Using CRISPR and pluripotent stem cells to determine osteoarthritis effector gene function at Newcastle University on FindAPhD.com

One more time. End DST. Thanks St. Louis on the Air for hosting. stlpr.org/show/st-louis-…

Professor Qing-Jun Meng and his team at The University of Manchester have further uncovered how the inner biological clock is involved in breast cancer spreading. This new knowledge could help us find new and better ways to treat the disease. breastcancernow.org/about-us/resea…

Out today! Circadian rhythms in proteome turnover, especially macromolecular complexes, which allow proteome renewal even under cellular proteostasis, osmostasis, and energy homeostasis constraints: embopress.org/doi/full/10.10…

Chondrocytes have multiple ion channels for sensing mechanical stimuli - in our latest study, Bob Nims MaybeItsBob & Daniel Palmer (w/Bo.博) used RNA-seq to analyze the complete chondrocyte "mechanome" in response to activation of TRPV4 or Piezo faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

Paper Alert! Our new work shows collagen IV variants act by collagen IV deficiency, hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease, a major cause of #stroke & #dementia eBioMedicine – The Lancet Discovery Science The Lancet UofG SCMH thelancet.com/journals/ebiom… a 🧵

Incredibly proud to share this work, almost 6 years in the making, out in Science Magazine!!! 🎇 We've known for over a century that eukaryotes of all kinds anticipate the seasons (think: hibernation, flowering, reproduction), but what about bacteria?🦠 science.org/doi/10.1126/sc…

The anti-aging impact of metformin (randomly assigned, with controls) in male monkeys after 40 months of treatment, a pan-omic clock assessment —~6 year regression of brain aging, with prevention of atrophy and enhanced cognitive ability —minimal effect on blood sugar —evidence

Major academic publishers are getting sued for unlawfully appropriating billions of dollars. Prof. Lucina Qazi Uddin, a neuroscientist at UCLA, has sued these six academic publishers Elsevier, Wolters Kluwer, Wiley, Taylor & Francis, Sage, and Springer Nature. The lawsuit

Congrats Ruhang Tang & Natalia Harasymowicz for our new PNASNews paper on gene therapy for fat-1, an enzyme that converts 𝜔-6 fats (frying oil/meat) to 𝜔-3’s (fish/nuts). Increased 𝜔-3:𝜔-6 reduced inflammation, osteoarthritis, and markers of cell aging! pnas.org/doi/10.1073/pn…

Congrats to Gabi Marushack and Alireza Savadipour & team for our latest The Guilak Lab paper showing that polyunsaturated fatty acids alter cell membrane properties & inhibit chondrocyte #mechanotransduction by #Piezo1 and #TRPV4. faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

Meng lab ventures into the kidney world with the Lennon lab at the WTCCMR and Biological Time MCR . We found that the #CircadianClock plays an important role in glomerular basement membrane homeostasis. Congrats to Becky who defended her PhD which included this work.

Our literature review ⏰ that accompanies the BSMB #ECR Award is now out in The International Journal of Experimental Pathology. Well done to Ask Møbjerg and Sara Dietz Pedersen for putting it together! 💪 #tendon #translationalmedicine #circadianclock onlinelibrary.wiley.com/doi/10.1111/ie…