Liyun Miao
@miaoliyun
Postdoc in the Giraldez lab, studying how pioneer factors reprogram the zygotic chromatin to orchestrate development
ID: 1158544102885142536
06-08-2019 01:03:33
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GeneAbacus is out! Finally released 😉 Count & profile reads in genes, chromosomes or constructs. Profile options adapted to Ribo-seq & CLIP-seq & mRNA-seq to MPRAs! github.com/vejnar/geneaba… #Bioinformatics Giraldez Lab BazziniLab Cifuentes Lab Miler Lee
It’s a cornerstone! LabxPipe is out! Easy genomics pipelines: mapping, gene count & trackhubs. Integrated with LabxDB. Examples & code: SourceHut git.sr.ht/~vejnar/LabxPi… GitHub github.com/vejnar/LabxPipe #Bioinformatics Giraldez Lab
Check out our preprint on how the pioneer factor GAF localizes to nuclear foci where it represses transcription! This was an amazing collaborative study with Shelby Blythe and Mustafa [email protected] led by grad student Marissa Gaskill. biorxiv.org/content/10.110…
Our work describing Chromatin Expansion Microscopy is now out in Science Magazine science.org/doi/10.1126/sc… Check out how we were able to visualize transcription, chromatin, and TFs with molecular resolution in developing zebrafish embryos to understand gene regulation!
🔬🧬 Excited to share our latest study science.org/doi/10.1126/sc… Science Magazine developing ChromExM which uses expansion microscopy to visualize the chromatin, transcription, RNA POL II and pioneer factor Nanog during genome activation.