🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

“Now that you thought that your paper is accepted, go and submit all the original gel images. And fill out all these other forms, please. The Materials table has to be in a separate file. Could you please select how many offprints you want to order?”

On this day in 1936, socialist poet Federico García Lorca was executed by fascist forces in Spain.

Remi Janicot and I wrote a review for Mol Pharm (ASPET) ASPET on optical biosensors for #GPCR signaling. We tried to make something useful for choosing what assays to use depending on the questions you have (I am told the link is for 100 free pdfs) molpharm.aspetjournals.org/cgi/reprint/10…

Using a Doritos ingredient is wizard level of cool. I am corroded by (healthy) envy. Time to look at the list of ingredients of Cheetos and Fritos to come up with a sequel. Achieving optical transparency in live animals with absorbing molecules | Science science.org/doi/10.1126/sc…

YES!!

Dedicated to all my fellow scientists. It is nice when you are reassured that your gut instinct was right.

“Nowhere else are the battles so fierce because nowhere else are the stakes so small” —Henry Kissinger, describing the academic world Academic Chatter™

Please RT and spread the word widely: Our department is hiring a tenure-track Assistant Professor in Global Change Biology (GCB), as part of a cluster hire in Global Change & Sustainability at Boston University: jobs.silkroad.com/BUCareers/Facu…

Yesterday the legendary Roy Haynes passed away at age 99… He was among the most recorded drummers in jazz. In a career lasting over 80 years, he played swing, bebop, jazz fusion, and avant-garde jazz. He is considered to have been a pioneer of jazz drumming… In this clip we

Check out this protocol for detecting endogenous GPCR activity in primary cell cultures using ONE-GO biosensors, by Mikel Garcia-Marcos Laboratory et al. STAR Protocols #CellBio2024 hubs.li/Q02_H8ZK0

Excited to share our latest on ELFN1 mechanisms, a dysfunction of which leads to a devastating neurodevelopmental disorder. Swan song of Henry A. Dunn. #GPCR , #Elfn1, Journal of Biological Chemistry sciencedirect.com/science/articl…

“You should never be comfortable, man. Being comfortable fouled up a lot of musicians.” — Miles Davis

“My guitar is my best friend.” — Django Reinhardt

Bad motherf*ckers

The emperor

We have innovated design of templates for CRISPR/Cas9 editing which allows efficient introduction of epitope tags in vivo. It is a simple hack which we hope to be broadly useful. Work by talented graduate student Chuanping Zhao. nature.com/articles/s4146…

I'm excited to share our lab's newest publication on the structure and pharmacology of GABA transporter 3 Nature Communications. Much to our surprise, GAT3 adopts an inward-open conformation in complex with the (moderately) selective antagonist SNAP-5114. #CryoEM rdcu.be/ei2KY

Our GzESTY paper is online. We optimized a cell based assay to sensitively detect GPCR activation in response to ligand application or in complex mixtures containing endogenous ligands. GzESTY was designed to aid in GPCR deorphanization efforts. nature.com/articles/s4146…