Just asked to write a research highlight for a Springer Nature journal (annual profits $500m). I have quoted my daily rate. Somehow I feel I won't get this commission, and someone will write this for free... we have only ourselves to blame.

Abrogate: to repeal (a law) or evade a responsibility. Alternative words are available if you are knocking out a gene function...

Magical conditions this morning kayaking off the St Andrews coast

The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease dlvr.it/T6dGyB

Filament formation activates protease and ring nuclease activities of CRISPR SAVED-Lon dlvr.it/T6dGyg

Read it (and weep)

An entire year of daily record-smashing sea surface temperatures, and no sign whatsoever of the trend ending.

Truly terrifying.

Productivity tip

A really interesting study of a minimal CBASS:E2 system

📢 There's still time to apply for a PhD studentship to evaluate the clinical prevalence and significance of antibiotic tolerance in Gram-negatives!
Open to UK students until 30th April.
Collaboration with Benjamin Parcell and PearsonLab
findaphd.com/phds/project/e…

Arguably the most granular analysis to date of future economic impacts from climate change estimates we will knock 19% off anticipated incomes by 2050 even if we slash emissions. If we don't we'll knock 60% off incomes and enter an era of global austerity. businessgreen.com/news-analysis/…

We have two new permanent academic positions available in Bristol Biochemistry, UK.

Please RT!

1st position 'omics related' at lecturer level
lnkd.in/e6A7wuR3
2nd Any Biochem/Biophys/SynBio topic at senior lecturer to Associate Prof.
lnkd.in/eErdPGCk

Great talk by ⁦Aleksei_Agapov⁩ on his ⁦Multi-Defence⁩ project studying the immune system of Pseudomonas ⁦Microbiology Society⁩