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Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity doi.org/10.1042/BCJ202… Our latest work hot off the press from Otago Biochemistry. Thanks Rinky Parakra, PhD, KD, @ItamarKass, Guy Jameson, SMW & LizL

Excited to share my latest paper in #JournalofLifeSciences on #Cesium binding in #protein #crystals based on work between @MSU_NatSci and Otago Biochemistry doi.org/10.36069/JoLS/… Consider #caesium in your #crystallography experiments to improve #diffraction or solve #phases.

Newly discovered #Staphylococcus aureus serine hydrolase probe and drug targets pub.iapchem.org/ojs/index.php/… My latest review of ten S. aureus protein targets for probe & drug development. Looking forward to new advances Matthew Bogyo Christian Lentz and myself Otago Biochemistry.

Really excited to have our paper describing mutations in histone H4 now out - a fantastic collaboration with Gijs van Haaften and lots of families around the world. Now investigating the mechanism thanks to Marsden Fund support!

Gijs van Haaften Marsden Fund Thanks also to Peter Mace for helping with the structural interpretations of these mutations within the nucleosome!

Taputapu kē! Dr Matthias Fellner🧑‍🔬 MatthiasFellner Otago Biochemistry University of Otago has been awarded a #MarsdenFund Fast-Start to study how #Staphylococcus aureus 🦠 use biofilms in antibiotic 💊 resistant bacteria #infection s🏥. #staph #AntibioticResistance royalsociety.org.nz/what-we-do/fun…

Bacterial biofilm therapeutics project wins Marsden Fund support ift.tt/Ylq0Vr9 A project investigating new ways to fight deadly bacterial biofilms has won a Marden Fast-Start fellowship for its lead researcher, Otago biochemist Dr Matthias Fellner. Matthias is seeki…

Otago researchers set to tackle health issues with Career Development Awards ift.tt/ED3hxJa From a global health crisis to Aotearoa’s health inequity – University of Otago projects awarded Health Research Council funding will benefit those at home and around the world…

$3.8 million to Otago researchers in Career Development Awards ift.tt/Zaz9o1D The Health Research Council has awarded 19 Otago researchers almost $3.8 million in Career Development Awards. These awards help launch research careers through a wide range of master’s and…

We are looking for an Assistant Research Fellow to create Staphylococcus aureus samples for metabolomics to identify the roles of serine hydrolases in biofilms (otago.ac.nz/biochemistry/n…) University of Otago, Dunedin, New Zealand. Starting in July Details: otago.taleo.net/careersection/…

We are looking for a Postdoctoral Fellow to create peptide tools for the treatment & diagnosis of infectious diseases at the University of Otago & Shanghai Institute of Materia Medica. Funded by New Zealand Maurice Wilkins Centre Starting September Details otago.taleo.net/careersection/…

One week left to apply #postdoc #position in #biochemistry on #research into #peptide & #enzyme via #phage in ##infectiousdisease at #university Otago Biochemistry in #NewZealand and #Shanghai #SIMM Details: otago.taleo.net/careersection/…

1. characterization of a highly conserved S. aureus serine hydrolase. pubs.acs.org/doi/10.1021/ac… Otago Biochemistry (Annabel Walsh) OtagoChemistry (Sutherland, Tan) & international collaborators A. Bakker, @mariovdstelt, Nathaniel Martin, Nadia Aftab, S. Dela Ahator Christian Lentz

Looking for a new covalent electrophile for serine and cysteine nucleophiles? Check out this great work by ⁦Jeyun Jo⁩ and ⁦Tulsi Upadhyay⁩ developing an oxadiazolone based probe for the S aureus serine hydrolase FphE. biorxiv.org/content/10.110…

Exciting news from our recent research with Tulsi Upadhyay on oxadiazolone-based probes targeting FphE, a S. areus specific serine hydrolase. This is a result of great collaboration with MatthiasFellner, the Valdez lab, Joanna Jaworek-Korjakowska, and the team at Matthew Bogyo lab.

Check out our latest covalent probes for imaging Staphylococcus aureus infections published J. Am. Chem. Soc.. Great work from Jeyun Jo and Tulsi Upadhyay and collaborators. pubs.acs.org/doi/full/10.10…

Thrilled to share the news!! Thanks Matt Matthew Bogyo, for giving this fantastic opportunity to work on this project. Enjoyed teaming up with Jeyun Jo, MatthiasFellner and all our collaborators 🙌 Thanks Emily C. Woods, Nikki Pedowitz, Sijie Wang for helping us with this project!!

Structures just released rcsb.org/structure/8T87 rcsb.org/structure/8T88 determined in collaboration with Stanford University Matthew Bogyo and my lab at Otago Biochemistry - JACS paper on Probes for Specific Detection of Staph Infections doi.org/10.1021/jacs.3… Jeyun Jo Tulsi Upadhyay +others

New Biochemistry paper about one of my favorite enzymes ever - Structural, Spectroscopic, and Computational Insights of the Ethylene-Forming Enzyme. Collaboration between MSU Biochemistry & Molecular Biology Michigan Tech and myself at Otago Biochemistry doi.org/10.1021/acs.bi…

Just out: Covalent isothiocyanate inhibitors of macrophage migration inhibitory factor as potential colorectal cancer treatments. Great collaborative effort between School of Pharmacy JoelTyndall , Otago Biochemistry and University of Otago Chemistry doi.org/10.1002/cmdc.2…