Incredible work from Ramona Weber is on BioRxiv now! Check out how a non-canonical translation initiation factor mediates reinitiation and involved in stem cell fate by shaping the synthesis of specific signalling factors. 👇🏻

Happy #womaninscience day! Ayse Seda Yazgili @IpekSelcen @justZeri Lale 🌷🔬🧬 Fabiola Valdivia Francia Clara Duré Ramona Weber @chiararick AnnaMallone and many more!

#AcademicTwitter

How can transcription and translation be coupled? We performed long-read sequencing and found a curious switch towards TOP-motif mRNA isoforms in cancer. The presence of a TOP-motif changes mRNA translation efficiency. Thanks to the whole Sendoel lab for your team spirit!

Happy to share the latest pre-print from our lab. A single-cell CRISPR based investigation into clonal expansion and early tumorigenesis. biorxiv.org/content/10.110… A great team effort with MoorLab and Stephanie Ellis

An honourable moment to present my poster at #EMBLprotein conference to William Merrick who started all by discovering #eIF2A nearly 50years ago, and we are still trying to find its function! Thanks to all for this meeting and exciting discussions #Sendoellab #EMBL EMBL Events

Publication by the Sendoel lab (Institute for Regenerative Medicine, University of Zurich) with first author Umesh Ghoshdastider "Exploring the pan-#cancer landscape of #posttranscriptional regulation" Cell Reports bit.ly/3REmSXl #RNA #Bioinformatics

Snowflakes and science at our traditional IREM retreat in the magical landscape of Sils Maria. Great discussions and a lot of fun with our invited guest from Vienna, Stephanie Ellis.

The dark proteome encoded by more than 7200 annotated sORFs is redefining our understanding of the human genome. Interested in how to detect microproteins? Check out Fabiola's recent review "No country for old methods". sciencedirect.com/science/articl…

Huge congratulations to Ramona for being awarded the prestigious Ernst Hadorn transitional fellowship, marking a first (and important) step towards an independent position! ernsthadornfoundation.org/ernst-hadorn-f…

I am excited to share our new preprint. Human tumor suppressor protein Pdcd4 binds at the mRNA entry site in the 40S, where it blocks the eIF4F-independent role of eIF4A during recruitment and scanning. biorxiv.org/content/10.110… #CryoEM #science #mRNA #ribosome

Check out Peter F. Renz incredible work published nature ! It has been a long journey and I’m so proud of him to finally have come to the end! Amazing science and amazing colleagues 🙌🏻

It was an exciting moment to share my PhD project on eIF2A at the Cold Spring Harbor Translational Control meeting. I met great scientists from all over the world, exchanged ideas and enjoyed the great location! Thanks to all organizers! CSHL Meetings #cshltranscon Sendoel Lab

Final day of the Ellis and Sendoel lab retreat in epithelial biology. Excellent presentations, exciting new ideas, wrapping up with a visit to Pisa.

Preprint alert 🔔 check out the latest biorxiv from my lab featuring in vivo single cell ribosome profiling in aged mouse skin! Big congrats to amazing scientist behind this hardwork Clara Duré !

I’m thrilled to share my very first first-author preprint and our lab’s latest work💫 Check out how we challenged eIF2A’s enigmatic role in translation and learn more about its novel role in RQC!⭐️ #RNA #ribosome #eIF2A #translation

PhDone 🥳🎓 The last few years was full of successes, failures, ups and downs, but also full of amazing people, countless talks, great conferences, incredible science and endless support from my supervisor and my thesis committee. Thanks to all people who helped me during PhD!