A Chemically Inducible Organelle Rerouting Assay to Probe Primary Cilium Assembly, Maintenance, and Disassembly in Cultured Cells dlvr.it/Sxgn9X

@pauldauenhauer Agreed, it’s an amazing achievement. I think too (👇) that’s why a commitment to good mentoring is so important. When the acquisition of funds simply to maintain that cycle becomes the overriding goal, then an emptiness creeps in. totalinternalreflectionblog.com/2023/10/29/a-r…

An amazing opportunity for those seeking to conduct postdoctoral research in Turkey. With international level salary and benefits; and a remarkable team of scientists! Last days to apply👇 nanobio4can.net KUTTAM Koç Üniversitesi TÜBİTAK SUNUM ibg TBOLab

Support Ahmed Alsaftawi, an exceptional PhD student in my lab @KocUniversity, as he raises funds to help his family in Gaza. Despite his fear every day, Ahmed Alsaftawi continues to inspire me with his dedication to cell biology. Please, spread the word. gofund.me/c7e6219d

Many thanks to Communications Biology and the editors for recognizing and featuring my science journey. Looking forward to further enriching this story with exciting discoveries together with my amazing team and collaborators. nature.com/articles/s4200…

I am extremely honored to receive @WellcomeTrust Early Career Award - the first-ever given to Koç Üniversitesi and Türkiye 🇹🇷! Grateful to my mentors Tugba Bagci Onder and Tamer Onder.It was pleasure working w/Beril Esin and excited for what’s ahead w/Erdem Ercan! #WellcomeTrust

Super excited about this. Congratulations Özlem Yedier Bayram !!!!

Huge congratulations to Özlem Yedier Bayram for receiving the early career award from Wellcome to further explore the mechanisms behind epigenetic regulation of cell cycle. I wish her and TBOLab members success in this exciting project👏 Koç Üniversitesi KUTTAM

I feel truly privileged to be part of such an incredible team. Excited to delve into the fascinating complexities of chromatin and cell cycle biology for the years to come. Stay tuned for exciting discoveries and insights!

Harvard Üniversitesi, Cemal Kafadar'ın Ortadoğu Araştırmaları Merkezi Direktörlüğü görevini sona erdirmiş. Araştırma Merkezi ve Kafadar, İsrail destekçilerince Filistin'i desteklemekle suçlanıyordu. Rezalet. Akademiye açılan küresel bir savaş var.

İstanbul’un kültürel mirasının bekçilerinden Mahir Polat, tüm riskler göz önüne alınarak tutuklu tutuluyor, sağlığına kavuşabilmesi için derhal #MahirPolatıSerbestBırakın !

#MahirPolatıSerbestBırakın

Functional Genomic Screens Reveal RBBP4 as a Key Regulator of Cell Cycle Progression in TMZ-Resistant Glioblastoma biorxiv.org/content/10.110… #biorxiv_cancer

Hot from TBOLab 🔥Check out the new preprint about TMZ resistance and its epigenetic regulation in glioblastoma. Congratulations to Ezgi Yagmur Kala and whole team 🥳

New preprint from my colleague Ezgi Yagmur Kala! She developed TMZ-resistant glioblastoma cells and identified key regulators using an epigenetics-focused CRISPR/Cas9 library screen. A great step towards understanding resistance mechanisms. 👏🧬🧠 TBOLab #BrainTumorStrong

🧬In Neolithic Çatalhöyük, family was built on social relations rather than blood ties. Genetic analysis shows that over time, co-residents were no longer genetic relatives. Female subadults were buried with 5x more grave goods. 🔍A surprising story of Neolithic social life.

🌾 Tarım, her zaman insanlarla birlikte göç etmedi. Yeni antik DNA çalışması gösteriyor ki, Batı Anadolu’da insanlar yerlerinde kalırken, tarım ve köy hayatı fikir ve pratikler yoluyla yayıldı.

Congratulations to Özlem Yedier Bayram and Tugba Bagci Onder for this beatiful work where they identified BRPF1, an epigenetic reader, as a key driver of Taxol (paclitaxel) resistance in triple‑negative breast cancer (TNBC). CRISPR knockout and chemical inhibitors sensitize resistant

Happy to share that our latest work on epigenetic regulation of chemoresistance is now online! We mimicked Taxol resistance in vitro and utilized genetic and chemical screens to identify epigenetic vulnerabilities nature.com/articles/s1227…

Our latest preprint is out! 🚀 We've engineered targeted virus-like particles (VLPs) to selectively kill glioblastoma cells using Cas9. A modular and flexible delivery strategy for cancer therapy. 👉 biorxiv.org/content/10.110… #VLP #glioblastoma #CRISPR #syntheticbiology #cas9