✨ #Dipraglurant is an #Orally Active #mGluR5 Negative #Allosteric Modulator for #Neurological Disease Research. 👉 For more detailed information: medchemexpress.com/Dipraglurant.h… 👉 immune-system-research.com/2024/06/26/dip…

🎈#Isatuximab is a monoclonal antibody targeting the transmembrane receptor and #ectoenzyme #CD38, a #protein highly expressed on hematological malignant cells, including in multiple #myeloma. 👉medchemexpress.com/isatuximab.html 👉 For more detailed information: ncbi.nlm.nih.gov/pmc/articles/P…

✨ #S130 is a Selective #ATG4B Inhibitor for Various #Cancers Research. #S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine #protease) with an #IC50 of 3.24 µM. 👉 For more detailed information: medchemexpress.com/s130.html 👉 cancer-research-network.com/2024/06/27/s13…

🔔 Related Product Recommendation: #OVA #Peptide(257-264) TFA, is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I #MHC molecule, H-2Kb. medchemexpress.com/OVA_Peptide__2… 👉 More informations: cell.com/molecular-cell…

✨ #GW0742 is a #PPARβ/δ Agonist for #Metabolic Disease Research 👉 For more detailed informations： medchemexpress.com/GW0742.html 👉 immune-system-research.com/2024/07/01/gw0…

Breakthrough in #CRC Metabolism!🔥 This research illuminates the characteristics, mechanistic significance, and diagnostic potential of #plasma and #fecal #metabolomes in CRC! 📷 pubmed.ncbi.nlm.nih.gov/39137727/

Comparison of multiple #cell #death modes. #Cuprotosis、 #Pyroptosis、#Ferroptosis、#Apoptosis

✨ #XRD0394 is a potent and specific dual inhibitor of two #DNA damage response kinases, ATM and DNA-PKcs. 🎈 #MCE Raleted Products: medchemexpress.com/xrd-0394.html 👉 For more detailed information: pubmed.ncbi.nlm.nih.gov/38588408/

Congratulations! 🥳 A recent article in Nature Immunology reports that the balance between PHD1 inhibition and CTT stimulation is crucial for transcription condensates, opening up a new perspective for precise regulation!🤩 pubmed.ncbi.nlm.nih.gov/39169234/

✨ #R162 is a Potent #GDH1/GLUD1 Inhibitor for Kinds of #Cancers Research R162 inhibits cell proliferation and #tumor growth potential of human cancer cells. 👉 For more detailed informations: medchemexpress.com/R162.html 👉 cancer-research-network.com/2024/07/01/r16…

🎈 Related Product Recommendation: #Nile #Red Nile red (Nile blue oxazone) is a lipophilic stain. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm. 👉 medchemexpress.com/Nile-Red.html 👉 For more detailed information: pubmed.ncbi.nlm.nih.gov/38151470/

📣 #Tideglusib (#NP031112) is an irreversible GSK3β inhibitor. Tideglusib has #IC50s of 5 nM and 60 nM for GSK-3βWT and GSK-3βC199A, respectively. 👉 immune-system-research.com/2024/07/04/tid… 👉 For more detailed information: medchemexpress.com/Tideglusib.html

New discoveries in #CARTs (chimeric antigen receptor T cells)👏 This week, a paper was published in Nature, and the authors' research established asymmetric cell division as a framework for understanding CART cell fate determination and in vivo persistence nature.com/articles/s4158…

📣 #MCE contains 900+ compounds targeting ant-fibrosis targets, can be used for mechanism research and drug screening of fibrosis diseases. 👉 MCE Raleted Products: Anti-Fibrosis Compound Library (HY-L185) medchemexpress.com/screening/anti… 👉 For more: pubmed.ncbi.nlm.nih.gov/33239795/

👉 Beta Actin #Antibody Beta Actin Antibody is a non-conjugated and Mouse origined monoclonal antibody about 42 kDa, targeting to Beta Actin. It can be used for #WB, #ICC, #IHC-P, #FC assays with tag free, in the background of Human, Mouse, Rat. 👉 medchemexpress.com/antibody/beta-…

✨ Through a comprehensive screening and validation process involving multiple models, ginsenoside Rg3 (Rg3) as a compound capable of enhancing cardiolipin levels is identified. 🎈 #MCE Raleted Product: HY-N0603 Ginsenoside Rg3 👉medchemexpress.com/Ginsenoside-Rg… pubmed.ncbi.nlm.nih.gov/39159293/

Recently, a paper published in Cancer Cell has highlighted that the organized interneuronal precursor-like state in the characteristic niche of #DHGH3G34 is a vulnerability, and it has also pointed out that #CDK6 is a promising clinically feasible target🌟 pubmed.ncbi.nlm.nih.gov/39232581/

🎈#RGD #peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) plays an important role in cell #adhesion, #migration, #growth, and #differentiation. 👉 medchemexpress.com/rgd-peptide.ht… 👉 For more detailed information: onlinelibrary.wiley.com/doi/10.1002/ad…

📣#Cetuximab (C225) is a human IgG1 monoclonal #antibody that inhibits epidermal growth factor receptor (#EGFR), with a #Kd of 0.201 nM for EGFR by #SPR. Cetuximab has potent #antitumor activity. medchemexpress.com/Anti-EGFR_Neut… 👉 For more detailed information: cell.com/cell/fulltext/…

🔔 #Britannin, a natural sesquiterpene lactone, is a potent #NLRP3 and #USP7 inhibitor with #anticancer and anti-#inflammatory activities. 👉 For more detailed information: medchemexpress.com/britannin.html 👉 cancer-research-network.com/2024/07/24/bri…