Our lab is looking for a lab manager. If interested, please send your CV and cover letter to [email protected] If you know someone exceptional please encourage them to apply! We are looking to fill the position quickly. RT much appreciated.

The January cover illustrates that the human proteome can be algorithmically mined to identify thousands of encrypted peptides with antibacterial activity. go.nature.com/3qOQ4Nn rdcu.be/cFsni [Paper]

Ft'd on the cover of Nature Biomedical Engineering, a new paper from Marcelo Torres, Marcelo Melo & César de la Fuente (@pennpsych/ Penn Microbiology/ Penn Bioengineering) describes how the human proteome can be algorithmically mined to identify thousands of encrypted peptide antibiotics go.nature.com/3LMoYz7

Our latest paper is out in iScience journal. We report the performance of our low-cost #COVID test in the field during the pandemic in Philadelphia. Congrats to all co-authors including ones I can find on Twitter Marcelo Torres Benjamin Abella, MD MPhil et al.! cell.com/iscience/fullt…

We have created self-propelled machines loaded with antimicrobials that can treat infections in vivo ACS Nano First step toward autonomous antibiotics. Super fun collaboration. Led by co-authors Xavi Arqué Marcelo Torres Tania Patiño Samuel Sánchez pubs.acs.org/doi/10.1021/ac…

Happy first mother’s day to the best mom and the love of my life, hope you liked my first handmade pie!

July 1 marks a decade of me leading a lab. Here are 10 important things I have learned...🧵

The idea of reintroducing extinct organisms into our world has captured the public imagination but is limited by ethical, technical, end ecological issues. What if we could instead “revive” molecules from the past to serve as potential therapies today? (THREAD 1/5)

Very excited to share our latest publication in Cell Host & Microbe 🎉 In this study, we delve into the fascinating world of extinct organisms and their hidden potential in combating modern microbial threats using cutting-edge machine-learning techniques. sciencedirect.com/science/articl…

A hybrid antimicrobial peptide (AMP) design derived from scorpion venom and parts of other naturally occurring AMPs leads to AMPs with increased antimicrobial activity and minimal toxicity in a mouse infection model and red blood cells. nature.com/articles/s4200…

Excited to share our latest Communications Biology Nature Portfolio. Inspired by LEGO, we built hybrid antibiotics that work in mouse models by taking building blocks from scorpion venom. Fantastic collaboration Ravi.Radhakrishnan Marcelo Torres and team! Link to paper: nature.com/articles/s4200…

(1/7)Antimicrobial resistance is one of the greatest threats facing humanity and novel antibiotics are urgently needed. Today Cell we report the discovery of nearly 1 million new antibiotics by mining the global microbiome. 🧫️🔬. cell.com/cell/fulltext/…

A full thread on the science later, but I'm very happy that, after 5 years of work, the AMPSphere manuscript is out at Cell Congrats to celiodias Marcelo Torres César de la Fuente Yiqian Duan Sebastian Schmidt Alvaro Rodríguez del Río Jaime Huerta-Cepas Bork Group at EMBL Heidelberg ... doi.org/10.1016/j.cell…

Excellent piece on our manuscript with from DW News also providing some broader context to the work /cc celiodias Marcelo Torres César de la Fuente dw.com/en/are-scienti…

(1/11) Antimicrobial resistance is one of the greatest threats of our time, and novel antibiotics are urgently needed. Today, we report in Nature Biomedical Engineering the AI-driven discovery of tens of thousands of antibiotics in extinct organisms. nature.com/articles/s4155…

Discovering tens of thousands of new antibiotics from #AI of proteins of extinct animals! nature.com/articles/s4155… @NatBME César de la Fuente Penn Medicine Penn Bioengineering Marcelo Torres Jackie Peng

Combatting superbugs using evolutionary record of microbial warfare Raman UChicago Biological Sciences highlights work of celiodias Marcelo Torres César de la Fuente Luis Pedro Coelho (in Shanghai 14-24 Oct) discovering antimicrobials by leveraging history of warfare w/in microbial communities cell.com/cell-host-micr…

New research out in Nature Biomedical Engineering uses deep learning to mine the proteomes of extinct organisms for the discovery of antibiotic peptides ft. Fangping Wan, Marcelo Torres, César de la Fuente (@pennpsych/ Penn Microbiology/ Penn Bioengineering) & Jackie Peng (UPenn GCB) Penn IBI tinyurl.com/3dys6dek

A report in Cell suggests "the existence of hundreds of antimicrobials in the human #microbiome amenable to clinical translation." César de la Fuente Marcelo Torres Hila Sberro #microbiota👇 cell.com/cell/fulltext/…

New research supports the existence of hundreds of antimicrobials in the human microbiome amenable to clinical translation ft. Marcelo Torres, Angela Cesaro & César de la Fuente (@pennpsych/ Penn Microbiology/ Penn IBI/ Penn Bioengineering) tinyurl.com/4k5vdsu5