Not yet tired of pandemics? Why not read about the one caused by Wolbachia, an intracellular alphaproteobacterium, that's affecting insects and nematodes. Read it here: biorxiv.org/content/10.110…

Safely sharing non-identifiable sequences from private cohorts of complete genome assemblies: privvg.github.io/2022/09/24/pra… (Or: How to build a global pangenome from siloed data)

Last day to apply for these roles with the Wellcome Sanger Tree of Life Programme Assembly Team!

Read our #DarwinTreeOfLife article for NatureEcoEvo, where we ask "Does #genome size matter?" For our scientists, trying to work out resources needed for each species, the answer is a resounding "yes!" Find out more: ow.ly/9frb50Luabw @KewScience Cibele Sotero-Caio Shane McCarthy

we are delighted to see the first of many WellcomeOpenResearch genome notes for Anopheles now out. this first one is a single insect PacBio HiFi assembly for the major malaria vector Anopheles funestus. wellcomeopenresearch.org/articles/7-287… 1/n

The complete sequence of a human Y chromosome biorxiv.org/cgi/content/sh… #biorxiv_genomic

I've been dying to tell you all! I'm going on a national tour in 2023 representing the Australian Institute of Physics Australian Institute of Physics Looking forward to meeting lots of people as the Women in Physics lecturer. aip.org.au/News/13010152

Here's a thread about our new preprint biorxiv.org/content/10.110… on human germline mutation.

I worked in Shane's team for 4 years. They were some of the best years of my life. One of the positions is to replace me. Our DToL project is wonderful. I'm still in the project, just in another position now. Apply today! Darwin Tree of Life

Delighted that our work on chromosome evolution in Lepidoptera is published today! ✨🦋

Delighted this is out, led by Brice Letcher , culmination of 10 yrs of work,started by Sorina Maciuca. New genome graph methods took a lot of work, but paid off, and Brice showed gene conversion between genes explained unusually deeply diverged lineages in 2 surface antigen genes.

First step in a community project to provide a uniformly assembled, annotated and searchable set of bacterial genomes, our preprint on our initial release of 1.9 million genome assemblies+taxonomic estimates. (figure compares with previous 661k dataset) biorxiv.org/content/10.110…

In this preprint, Aylwyn Scally, Richard Durbin and I present evidence for deep population structure shared by all modern humans biorxiv.org/content/10.110… Aylwyn Scally Richard Durbin

Interesting #AssemblyCuration today Wellcome Sanger Tree of Life Programme. HiC-phased diploid assembly of a dragonfly. Curating both haplotypes together in a merged map. Pics show X and Y sex chromosomes that were mashed up between the haps and also lots of false duplication by hifiasm to be removed. 🧵

Excited to announce our new review: Beyond the Human Genome Project: The Age of Complete Human Genome Sequences and Pangenome References. w/ @BenedictPaten Rajiv McCoy Karen Miga Eimear Kenny et al. annualreviews.org/content/journa…

Our new preprint is up - “Insights into non-crossover recombination from long-read sperm sequencing”! biorxiv.org/content/10.110… Thread: 1/

Working on a very cool Darwin Tree of Life assembly today. Haplotype resolved assembly of PENTAPLOID Rosa agrestis. They have asymetric meiosis with two chroms forming bivalents and the other three inherited as univalents through the egg. Spot the bivalent pairs in the HIC map.