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Ouch.

McMurray lab and CSD Graduate Program graduate/alumnus making us all very proud 👇🏽👇🏽👇🏽

Just submitted my 26th manuscript peer review of 2024. That's one every <10 days. I think I am going to take a little break now...

I was reminded that most proteasomes reside in the nucleus and I was like, "How did I forget that?" and then I was like, "Because it's basically never shown in any figure about the proteasome"! Are cytoplasmic proteasome substrates imported into the nucleus for degradation? 🧐

Yay, #SEPTforSEPTINS is here again!

MBoC Call for Papers on Evolutionary #CellBiology. Submit an article by Dec 30 to lead editors: Gautam Dey, @EMBL MichaelMcMurraylab, CU Anschutz Medical Campus @mcmomany, UGA OnishiLab_Duke, Duke University Courtney Schroeder, @UTSWNews Holly V. Goodson, University of Notre Dame Submit: molbiolcell.org/evolutionary-c…

Register here: meetings.embo.org/event/25-clima… for the 13-16 April 2025 Lisbon. Please join us!

I was an ableist asshole when I first became a teacher. Because that’s what I was taught! In my defense, academic institutions told me a strict attendance policy was required. What changed my perspective & my assessment criteria? Disabled students 🧵

1. Check out our MS just out! Amazing Mauricio Aguilar developed a new ML pipeline that identifies ribosome pausing sites as an Anomaly Detection problem to overcome spurious signals that arise when analyzing RiboSeq data. science.org/doi/10.1126/sc…

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A trove of insights! I found an ArgPro dicodon exactly where we’d predict to drive pausing in Cdc12, the septin we think is slowly translated, in a loop where the α2 helix would be exiting the ribosome & closing the α-β sandwich where other Frydman lab data showed chaperones bind

News that our paper was accepted today somehow doesn't bring the same sense of satisfaction or joy...

Ok, a second paper accepted in the same week is helping a bit, I must admit 😐

Sadly, your email does NOT find me "impelled by a fervent scientific curiosity in the field of Plant Biology" hence I'm afraid I will not "avail this opportunity to share [my] scientific excellences" but I salute your farraginous lexicon 😄😄 (no disrespect to plant biologists)

We are still recruiting postdoctoral fellows! We are looking for individuals interested in human pathogens and their response to antifungals. An NIH R01 fully funds this project. This project involves genetic, cell biology, microscopy, and proteomics approaches! Please RT 🙏🏽

MBoC Call for Papers on Evolutionary #CellBiology. Submit an article by Dec 30 to lead editors: Gautam Dey, @EMBL MichaelMcMurraylab, CU Anschutz Medical Campus @mcmomany, UGA OnishiLab_Duke, Duke University Courtney Schroeder, @UTSWNews Holly V. Goodson, University of Notre Dame Submit: molbiolcell.org/evolutionary-c…

My lab at UCSF (hsiunglab.org) is looking to recruit multiple postdocs across the spectrum of wet/dry lab interests to contribute to our research in synthetic gene regulation, combinatorial genetics, and tissue biology (including liver biology and immuno-oncology). We

Sure smells like a scenario for septins, wouldn’t you say SpiliotisLab Ewerslab ?

Check out our MS describing the in vivo cycle of chaperonin TRiC/CCT, in a wonderful collaboration with Martin Beck's lab: nature.com/articles/s4158… 1) The study established TRiC's important function in folding newly translated proteins and defines its ATP-driven cycle