New publication by McCabe Lab in Nature Communications Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau. Congratulations to all the authors ! actu.epfl.ch/news/protein-t… #epfl

A new study by McCabe Lab EPFL Brain Mind Institute reveals how a malfunctioning protein complex can lead to the buildup of toxic forms of Tau, a protein involved in Alzheimer’s disease and other neurodegenerative disorders. actu.epfl.ch/news/protein-t… #epfl

The cruelest cut: new lab National Communication Association paper nature.com/articles/s4146… shows retromer deficiency (implicated in #PD & #Alz) increases human Tau truncation & toxicity. We develop tools to quantitate Tau neurodegeneration with single synapse/axon resolution in intact #Drosophila brains.

Delighted our Tau & Retromer study is published nature.com/articles/s4146… led by the indefatigable Jamshid Asadzadeh. Grateful to our collaborators Graham Knott, Scott Small and Ismael Santa Maria & for the support of EPFL EPFL BIOP, Bernard Schneider and the EPFL Gene Therapy platform.

Nice article about our work on Tau and Retromer - nature.com/articles/s4146…. You can also watch a visualisation of our new method to quantitate single axon neurodegeneration within #Drosophila brains here - youtube.com/watch?v=Z5MIPG…. EPFL Brain Mind Institute EPFL Life Sciences EPFL Center for Imaging

PhD student Marine Van Campenhoudt appeared on @RTScqfd on RTS today to talk about our recent work led by Jamshid Asadzadeh on neurodegeneration - go.epfl.ch/16944f. If you didn’t catch it live, you can listen to it here (en français) - rts.ch/la-1ere/progra…

EDNE student Marine Van Campenhoudt appeared on @RTScqfd on RTS to talk about the recent publication of the McCabe Lab on neurodegeneration led by Jamshid Asadzadeh - go.epfl.ch/16944f: Listen to it here: pages.rts.ch/la-1ere/progra…

Tangled Fly Eyes–Fruit fly model of aggregated #tau– protein implicated in #Alzheimer's–reveals affect on #nerve signalling. Image & research by Jamshid Asadzadeh et al Brian D. McCabe lab EPFL Brain Mind Institute in Nature Communications. Read more on bpod.mrc.ac.uk/archive/2022/1… with MRC Laboratory of Medical Sciences (LMS) & Ruth Williams

Thanks to @BPoD_mrc for selecting our scanning electron microscope images of #Drosophila eyes, generated by Jamshid Asadzadeh and Wei Jiao together with Graham Knott & EPFL BioEM nature.com/articles/s4146…, as their image of the day. McCabe Lab EPFL Brain Mind Institute EPFL Life Sciences

Are you an #undergrad from anywhere in the world? Want to spend your next summer doing cutting-edge research in biology in Lausanne, Switzerland? Applications are now open for our renowned Summer Research Program in Life Sciences! EPFL Life Sciences EPFL epfl.ch/schools/sv/edu…

Very honoured to be the new director of the BMI EPFL Brain Mind Institute & thank you all for your kind words of support. Neuroscience EPFL cannot fail but to prosper with such tremendous colleagues. I eagerly anticipate the discoveries we will make together.

👏 Congratulations to #MSCA #EPFLglobalLeader fellow Rebecca Smith on her recent publication!

Gratifying that we, with many others, could contribute to this important work doi.org/10.1172/JCI165… and aid in modelling CerTra in #Drosophila. Hopefully this is the first rung on the ladder towards understanding and treating this novel neurodevelopmental disorder.

Glad to have our submissions included and many congratulations to the outstanding winning images and videos.

Delighted to welcome the many visitors to our lab today to learn about motor ageing in #Drosophila as part of #PortesOuvertesEPFL. A special thanks to our hardworking presenters Evelyne & Greta and to all the supporting lab members.

Delighted to contribute to the study of our Lausanne colleague @mc_gambetta , and co-authors, of long range meta-domains governing gene regulation in #Drosophila neurons - cell.com/cell/fulltext/…

The McCabe Lab group in @brainmind_EPFL identify a protein that can delay the decline of motor ability during aging - actu.epfl.ch/news/a-key-pro… EPFL Life Sciences EPFL Schweizerischer Nationalfonds (SNF)

Thank you to Target ALS for supporting the #ALS research of the McCabe Lab in the EPFL Brain Mind Institute EPFL Life Sciences together with our collaborators Bernard Schneider and Sabine Liebscher.