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Happy to share new work Fraternali Lab led by Dongjun Guo - exploring how antibody heavy and light chains form specific pairs. We fine-tuned an antibody language model to predict pairing, and asked how pairing propensities change during B cell maturation and in diseases.

Lactate: A key regulator of the immune response dlvr.it/TJXDFD

Our lab's latest article just published Clinical & Experimental Immunology. Using antibody engineering & preclinical models, we show a close cooperation between activating & inhibitory FcγRs helps boost immune responses following immunization. Curing Cancer UoS Southampton Medicine BioInvent International academic.oup.com/cei/article/do…

B-cell subsets: How do we define them? 🧬 Advances in mass cytometry & scRNA-seq reveal more diversity than ever, yet challenges in identification remain. 🔍 Learn about gating strategies & B-cell changes in inflammatory disease: bit.ly/4hiSvyT #Immunology

🦠 How do gut cells shape infections? This study, part of the Review Series - Organoids to Study Immune Cells Development and Function (Ed. Joana Neves), uses organoids to reveal how pathogens target specific cells! 🔬 Read more: bit.ly/422Z96U #immunology #organoids

Happy to share our latest reflections Trends in Immunology on our favourite cells: IL-1b+ macrophages 🔥🔥🔥 Molecular, spatial, temporal, functional properties in cancer and beyond.. it's all in there from the awesome nicoletta caronni, Federica and Luca Frosio. cell.com/trends/immunol…

🧬 Vaccine response isn’t just about antibodies. This study shows pediatric AIIRD patients generate robust CD4+ T-cell responses post BNT162b2 vaccine—comparable to healthy peers. Read now 🔗 bit.ly/3XSCZ61 #CelebrateVaccines

10 years after the tetanus vaccine was introduced to the UK vaccination programme, tetanus had almost disappeared in children under 15 🌟 We’re celebrating the success of the tetanus vaccine in this week’s #CelebrateVaccines blog! 🔗 Click here: bit.ly/42CgrZN

🔬 Explore the link between microglial morphology and function! 🧠 Discover how changes in microglial shape reflect inflammation and tissue damage in the CNS, and why combining histological and genetic approaches is key for deeper insights. 👉 Read more: bit.ly/4ieWE7z

🧬 Our NEW #immunology course is open for registration! 🔹 Understand the immune system, vaccines and #immunotherapies 🔹 Interactive, expert-led learning 🔹 No prior knowledge needed 📅 Taking place online, Thursday 19 June Register now ➡️ bit.ly/4itgnAk

🌍 This World Immunisation Week, let’s celebrate diversity in science! Apply for the BSI’s EDI grant by 9 June to promote inclusion within the immunology community. Your ideas can make a difference! 👉 Learn more and apply: bit.ly/3gYExJv #WorldImmunisationWeek #EDI

Applications for our funded PhD position are now open! ucl.ac.uk/work-at-ucl/se…

Why do some children develop MIS-C after COVID-19? Could rare genetic mutations be to blame? A new review connects IFN-I pathway defects to severe SARS-CoV-2 outcomes. 🔗 bit.ly/42Mc5iZ

Need to learn the basics of immunology? Our new 'Foundations of Immunology' course on 19 June is designed for scientists, HCPs, and students who want to understand one of the most vital and fast-evolving areas of science and medicine. ➡️Register now: bit.ly/4itgnAk

We all know how important British Society for Immunology is so here I am trying to contribute a bit 😁 I'd love to represent ECRs in the BSI Forum and voting is now open so please click below and vote vote vote. I have to admit the other candidates look great too! 🙌 immunology.org/news/bsi-commi…

💡 From gut immunity to co-culture systems, this organoid-focused review series in CEI, led by Joana Neves, brings together foundational knowledge for immune cell research. 🔗 bit.ly/4jL01o3 #ImmuneResearch #Organoids #Immunology

It’s #CoeliacAwarenessMonth: Discover how B cell subsets differ in children with type 1 diabetes and/or celiac disease. This study sheds light on immune shifts that could impact disease management. 🔗 bit.ly/43qFUVk

If you hadn't had a chance to do so already please have a read through our statements for the ECR reps on the BSI forum and vote 😁😁 voting ends June 3rd and would much appreciate a vote 😊🙌🙏

🔥 HLH decoded! 🔥 📢Dive into our latest review Clinical & Experimental Immunology British Society for Immunology exploring the tangled web of HLH/MAS pathophysiology with fresh insights from animal models. Bench to bedside💥 #MedTwitter 🧵#Immunology nerds👇 #HLH #MAS #CytokineStorm 📰 doi.org/10.1093/cei/ux…

Got ground-breaking translational or clinical immunology research? 🧬 We welcome high-quality studies that advance understanding of human disease and clinical practice. Submit your work today: bit.ly/443pf8s #Immunology #ClinicalResearch