“Research at the interface of chemistry and biology has always been where I practice, and having a Nobel Prize in chemical biology is really great for the field,” said Bertozzi. “The field is not so old, but the impact is clear.” news.stanford.edu/2022/10/05/car…

Today’s incredible news is exciting on so many levels! As a lab, we use Click chemistry daily & it has transformed our research. When I was a grad student @CarolynBertozzi was the most supportive member of my College of Chemistry committee and a rising female star I looked up to....

Welcome to the FUNR Team Scott! We are already off to a great start with you on board 🧬🔬🔧

Been waiting to see this beautiful work in print from @drcmwoo and Matt Pratt groups. They find that C-terminal cyclic imides (from backbone cyclization of Asn/Gln residues) are natural ligands for the E3 ligase cereblon--thalodimide is a mimic. #PROTACS nature.com/articles/s4158…

Excited to reveal an essential function for protein degradation and quality control in development: shaping network dynamics to control gene expression and cell identity! Many implications for #TPD. A little thread. biorxiv.org/content/10.110…

Our first preprint is out! Led by Rohith Rajasekaran (Rohith Rajasekaran): “A programmable reaction-diffusion system for spatiotemporal cell signaling circuit design” A visually stunning toolkit to build cellular radios that probe or control cell biology. biorxiv.org/content/10.110…

Congratulations to post-doc Yen-Li Li for her work on the structure of HIV-1 Vif in complex with human A3G. A fantastic collaboration with Caroline Langley , @nchesarino, @memerman of #FredHutch and Ignacia Echeverria, Caleigh Azumaya, Yifan Cheng of #UCSF. rdcu.be/c5bst

If you're at Stanford and want to hear about and discuss eLife - the journal's new model and broader challenges in science publishing, please come. I look forward to a fun and spirited conversation.

I’m super excited to share a preprint of my graduate work, out now on bioRxiv! If you are interested in E3 ligases, chemical biology, or proteostasis, this one’s for you! Check it out at doi.org/10.1101/2023.0…, or see below for a summary 👇

👻 Your Worst Drug Discovery Nightmare?? 😱 It's a dark and stormy night... You hear a ping on your phone - it's a work e-mail. From: Billy Byologist INTERNAL: Exciting New Data From HTS!!!

This week was a milestone in #Crinetics history as we celebrated the grand opening of our new state-of-the-art facility, which will allow our scientists to further develop meaningful therapies for patients. Thank you to all those who joined us for this momentous occasion.

So excited to see our work on "Profiling the proximal proteome of the activated μ-opioid receptor" using APEX-based proximity labeling and quantitative mass spec published today. It is the result of an amazing team effort! nature.com/articles/s4158… #TeamMassSpec #Proteomics #GPCR

Happy for these two guys who just graduated last week. They started in the lab 2 days apart and finished 1 day apart. Congrats to Franco Faucher and John Bennett. On to many more great things as PhDs.

the lab is recruiting scientists HHMI | Janelia! we are particularly excited about engineering fluorescent proteins and biosensors using high-throughput assays and machine learning. questions? please get in touch!

Interested in learning how dyes might help in characterizing protein activity? We're excited to share the development of a protein-adaptive DSF platform (paDSF), a dye-based method used to interrogate stability, dynamics, and ligand binding! go.nature.com/4ajNRNp

Thrilled to see our paper "A Proximity Proteomics Pipeline with Improved Reproducibility and Throughput" published! It describes the automated enrichment of biotinylated proteins in a 96-well plate format for spatial proteomics and protein interactions. embopress.org/doi/full/10.10…

I’ve successfully defended my PhD thesis! Huge thanks to my incredible advisor, Alice Ting, for the unwavering support, and to all the amazing tinglab members for creating such a fantastic lab environment. I feel so fortunate to have been a part of the tinglab.

Today is World Malan Syndrome Awareness Day! The number 19 is significant for our community as the NFIX gene is located on Chromosome 19. Today, we honor the strength and resilience of those affected by Malan syndrome—our beautiful sunflowers. 🌻 #MalanSyndromeAwarenessDay2024

Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP ⁦Gestwicki Lab⁩ ⁦Institute for Neurodegenerative Diseases⁩ nature.com/articles/s4146…

Excited our final version of Christine Isadora Ng's work on targeted protein relocalization is out today @nature! Molecular control over protein localization could offer new opportunities for therapeutics and biological discovery. Sarafan ChEM-H Stanford Chemistry nature.com/articles/s4158…