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Personalized medicine in #COVID19? Immunotherapies in critically ill adults with #SARSCoV2 could be enhanced with pt selection based on host immune response characteristics. Substudy within remap-cap 📎 rdcu.be/cXgRo & its editorial 📎 bit.ly/3ywuOzD #FOAMcc

Writing a great abstract can be tricky! This writing template by nature is super helpful 👉

The best review of tissue macrophage cells—critical for both preserving health and their role in many diseases—that I've seen cell.com/cell/fulltext/… Cell Miriam Merad, MD, PhD Lipschultz Precision Immunology Institute @park_mstreet @AymericSilvin @realFlorentGinhoux SinaiMSTP

Thrilled to share the main story of my PhD work! We show that ABCs (T-bet+ B cells) are potential mediators of EBV's contribution to MS. Previously associated with viral infection and autoimmunity, here we examine ABCs in these two contexts together. doi.org/10.1126/sciadv… 🧵

Two post docs doc positions in the @msh_manu lab!

As an academic writing coach, here are the 7 mistakes I see supervisors and PIs make in the process of co-writing a paper with their PhD students or mentees. A thread. 🧵 #AcademicChatter #newPI #PhDchat

Acknowledgments that should have been in my PhD thesis: I drank a ridiculous amount of Yorkshire Tea. Good things or bad things ended with a cuppa so thanks to these guys for getting me through. Any unusual acknowledgements you would have put in?

1/ Together with the COVID Human Genetics Effort, we are happy to report our finding of inborn errors of the OAS-RNase L pathway in children with MIS-C #Misc #Pims in Science Magazine (science.org/doi/10.1126/sc…)

Thanks for all the congratulations post viva! Means the world and I got to celebrate on the night with the awesome guys! Many people pst and present to thank for last 4 years. Very blessed and humbled to have worked with such incredible people

First morning at Banff inflammation workshop 2023 #BIW

So excited to share my work from the last 3 years 🥳🎉🥳 We developed a new method to analyze multi-condition single-cell data and find differential expression neighborhoods for arbitrary exp. designs. All the details (and some cool diff. geometry) at biorxiv.org/content/10.110…

Happy to present my recent work - a cluster-free method for DE testing, leveraging overlapping neighbourhoods in the graph representation of sc-data (aka miloDE): biorxiv.org/content/10.110… . A little thread below describes the motivation and suggestions on interpreting the results.

COVID-19 subphenotypes exist, impact patient outcomes and intervention outcomes. Understanding the underlying immunology and mechanisms could inform precision medicine trials of the future! ISICEM @msh_manu Jennifer Rynne link.springer.com/article/10.100…

Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes. elifesciences.org/articles/84391…