Quick recap of interesting takes (some of my own and some of others) on how Trump and RFK policies will impact bio and health investing. Cuts in NIH (SBIR, STTR, others) will impact early biotechs that fully or partially rely on non-dilutive funding. Without it, these startups

I'm attending a dinner to discuss accelerating research and solutions to environmental toxins. This Wed 4/30 in Berkeley. A couple spots opened up. Which researchers, founders, investors, philanthropists should we invite? DMs open.

We’re co-hosting Night of Neurotech at SF Deep Tech Week with E11 Bio! This year we're featuring founders & scientists exploring far-future neuroscience tech for human augmentation. Neuroscience isn't just for healing; it will elevate everyone's lives. June 24th, 5-8pm Sign up:

With so many conversations about America's broken healthcare system, one of the few realistic shifts I can think of is getting life companies to cover medical bills. Life insurers pay when you die, so they are the few ones that actually want to keep you alive. Singapore did it

It really pays to be on the forefront of innovation For instance, Vertex was able to secure their first deal with Chugai, valued at $30M ($74M today), with just an idea of designing a molecule against FKBP, and some early X-ray crystallography work. They didn’t even have working

more Apollo programs and Manhattan projects, less broad research initiatives

Join us next Tuesday for Night of Neurotech during SF Deep Tech Week! Fantastic speaker lineup: ​1. Ying-Hui Fu, Professor of Neurology at UCSF 2. Nathalie Gouailhardou, CEO of Neurode 3. Laura 🌲 ⛰️, CEO of Cradle 4. Rahul Chhabra, CEO of stealth BCI co 5.

Easier to establish a Mars colony than fix the Federal government. Easier to build crypto than fix the banking system. Easier to attempt network states than fix liberal democracy. Easier to homeschool with AI than fix schools. Easier to read Substack than fix media. Funny

time love memory

Just got back from MAPS’ Psychedelic Science. A few reflections: The past few years have been of wild swings: ridiculous hype, then pure defeat. This year felt like things settled into grounding and humility. At PsyMed, we wrote most of our psychedelic checks a few years ago.

Tonight’s neuro event SF Deep Tech week with ⁦Andrew Côté⁩

Neuroscience as a stepping stone to flourishing Almost every psychiatric and neurological condition is rising. It’s an existential threat hiding in plain sight. We need breakthroughs in brain health. Yet I’m increasingly excited about neuroscience expanding (not shifting) from

Fun fact: Some people have a rare genetic mutation that lets them thrive on just 4–6 hours of sleep a night - and tend to live long, healthy lives with lower rates of diseases including Alzheimer’s. UCSF’s Dr. Ying-Hui Fu studies these natural short sleepers. In our new Business

Are we headed toward a technology revolution in therapeutic BCI? I just wrote this piece about why I believe neurotech will become an indispensable tool for addressing the growing mental health crisis and become as common as personal computing. 🧵 open.substack.com/pub/brainjacob… #BCI

This is a personal, honest, optimistic take on neurotech as a driving force in human flourishing. Super proud to partner with Jacob Robinson motif neurotech