Two years now since I moved on to new ventures up North but great to get our latest work from my time in the Wigley lab Structural and Synthetic Biology in collaboration with the @Dillingham_Lab written up. Many thanks Mark, always a pleasure!🤞 for publication! biorxiv.org/content/10.110…

Paper published just in time for Xmas! 🥳 Thanks to the editors and reviewers, and @Dillingham_Lab for the enjoyable years working together on the project. Amazing seeing the diverse ways how phage proteins have evolved to target bacterial machinery. doi.org/10.7554/eLife.…

Excited to share our latest paper on amyloid fibril structures of beta-2-microglobulin, formed from the native folded state! Different fibril assemblies with a common subunit fold. Was an enjoyable team effort, I mostly just had to sit at the computer :) nature.com/articles/s4146…

🚨New preprint from the Aylett group Structural and Synthetic Biology Imperial Department of Infectious Disease 🚨 Happy to share this work, which formed the final chapter of my #PhDone thesis, on developing a 3D-printable flow-cell device to capture samples for EM direct to grids from lysate 🧪✨

Very happy to share our new paper out today in Nature Communications! With Stephen Muench, Robert Eady, Svetlana Antonyuk and Samar Hasnain, we present a 2.2 Å cryo-EM structure of qNOR, a membrane protein in pathogenic bacteria that breaks down host nitric oxide: rdcu.be/dd9cT 🧵

Released EMDB - EMPIAR @EBI & published nature, the 2.7 Å #CryoEM structure of core SusCD transporters forming stable glycan-utilising machines; important components for nutrient acquisition by colonic microbiota. Study by Neil Ranson et al Understanding Life in Molecular Detail emdb-empiar.org/EMD-15292 #EMDB

In situ amyloid in Alzheimer's brain! These tomos still blow my mind 🤯. Grateful to work with the best team Joshua Jenkins Nayab Tom Yehuda Halfon 🏳️‍🌈 @drrenefrank RadfordLab @JeroenHoozemans #teamtomo and to all those who donate their brains to science ❤️ biorxiv.org/content/10.110…

Big news! Proud to announce that the Louros Lab will be opening doors in December 2023 at UT Southwestern (utswCAND; The Department of Biophysics at UT Southwestern; UT Southwestern O'Donnell Brain Institute)! There will be openings at all levels so reach out or stay tuned if interested in joining! (1/4) #AssistantProfessor #newPI

Just in time for Christmas! Excited to see our fibril structures published, showing changing polymorphism of IAPP during the course of amyloid assembly. As always, brilliant team effort from the amyloid team, thanks all The Astbury Centre Neil Ranson RadfordLab sciencedirect.com/science/articl…

Pleased to share this story on gamma synuclein made possible with great collaborators... Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid | PNAS pnas.org/doi/10.1073/pn…