✨NEW features on MARRVELv1.2✨ 🎋 You can now search with amino acid changes (IRF2BPL:p.Pro372Arg) 🌻 gnomAD’s pLI and o/e metrics 🍄 Pathogenicity prediction scores including CADD, REVEL, M-CAP, PolyPhen-2, GERP, and phyloP

If you work on DNA break repair involving the #NHEJ pathway, there are a number of #drosophila LIG4 (Ligase 4) reagents, including tagged ORFs and a UAS driven #human LIG4 #cDNA available at #DGRC. #MARRVEL it here: ow.ly/qrwU50u2EEh

Did you know that you can search MARRVEL.org starting with a model organism gene name??? 🐭🐟🐝🐸🐛 marrvel.org/model

I was responsible for at least 50 of page visits today to this MARRVELous resource. 💯 Exactly what you need to know about every gene when doing gene review for genetic predisposition. MARRVEL #genetics

Thank you to the 1600+ users that visit MARRVEL.org each month! 👩‍🔬👨‍💻👨‍🎓👩‍💼 We have exciting updates coming up in a few months. Meanwhile, please keep sending feedback and suggestions our way! User feedback is what decides which features will be added 😁

Thanks for helping me reach 25 followers! Who else do you think should be following me?

We are designing a new mobile version of MARRVEL! What do you like or don’t like about the current one?

A protocol: Using MARRVEL v1.2 for Bioinformatics Analysis of Human Genes and Variant Pathogenicity …rentprotocols.onlinelibrary.wiley.com/doi/full/10.10…

MARRVEL dev team will be presenting a poster at #ASHG19! ASHG See you in Houston!

How can you identify which variants are pathogenic within human sequencing data? Try using Model organism Aggregated Resources for Rare Variant ExpLoration (MARRVEL)! Learn more in #CurrentProtocols in Bioinformatics: buff.ly/2y2pnsi Julia Wang, MD PhD MARRVEL Zhandong Liu

Check out the National Human Genome Research Institute (NHGRI) YouTube channel. Tons of recorded talks by leaders in the field. Today I saw on my YT feed Julia Wang, MD PhD 's talk on the MARRVEL web tool for rare variant exploration. Great work! Rare moment where Twitter and YouTube collide. youtu.be/Wz03eybmV98

💥Welcome to MARRVEL 2.0 beta beta.marrvel.org💥 ⁉️What's new⁉️ 🌟Revamped design and data display🌟 💬"MARRVEL's comment" to assist with data interpretation💬 📄Bulk search(VCF or list of gene names)📄 💊Drug information from IDG Pharos 💊

“Underpowered” for what? Very rarely is the observational RNA-seq the end of the line. It’s often the beginning of the question, especially in pertubable (ha) systems. biorxiv.org/content/10.110…

Molecular Research on Rett Syndrome and Related Disorders 2.0 mdpi.com/si/112947 #mdpiijms via IJMS MDPI