We are all walking mosaics of genetically distinct cells.

Every cell acquires around one mutation each division after fertilization, resulting in a vast amount of genetic diversity across all the cells in our bodies by the time we are born.

Mendelian causes of autoimmunity -> the #lupus phenotype! A fascinating (disease) syndrome #IEI , #RareDisease #Genetics with Maud Tusseau Plassart Samira Jade Cognard Sarah Benezech Liliane Khoryati Sébastien Viel Frederic Rieux-Laucat LYACTS-CIRI, Still so much left to uncover.

In a new paper in Nature Genetics, scientists from MRC Epidemiology Unity, University of Cambridge, report a new obesity gene--BSN (nature.com/articles/s4158…). Loss of function mutation in BSN causes an extreme form of obesity that is reminiscent of the weight gain associated with

Why Human Technopole? Located in beautiful #Milan , HT offers collaborative research environment and cutting edge facilities. Join a diverse community of scientists to work together on many aspects of B cell immunology!

What a pleasure to host Mégane Brusson from Institut Imagine! very nice Paris Postdocs Seminars seminar today at Institut Cochin ⭐️ Thanks Mégane for sharing your cool results with us Hugo Barreto Suzanne Faure-Dupuy (she/her)

New treatment will transform people's lymph nodes into ‘mini livers’

The first person has received the therapy, made by @LyGenesis, as part of a trial for people with liver failure and can’t get a transplant.

For nature, w/ Valérie Gouon-Evans Michael Hufford
nature.com/articles/d4158…

We are #hiring #postdocs in Paris at INEM NECKER, Université Paris Cité, Inserm, CNRS 🌍 !

Single-cell atlas of the SI throughout the human lifespan demonstrates unique features of fetal immune cells - So excited for this to be out. Lead by our talented postdoc Weihong Gu. ⁦Bunmi Olaloye M.D⁩ ⁦Yale School of Medicine⁩ ⁦⁦Yale Pediatrics⁩ sciencedirect.com/science/articl…

This isn’t terrible news. Until we can pay and treat our postdocs better, they should go find the other great opportunities out there.

Just. Share. Your. Plasmids.

Enough with the MTAs. It's the age of synthesis. The material doesn't matter and all you are really doing is saving your peers time and money. The thing, once constructed, is an infinitely renewable resource. Just share it.

Don't be weird.

Great to see this paper from Emmanuel Martin & Sylvain Latour's Lab Institut Imagine out now in nature. 1st report of IL27RA deficiency & role of IL27 in host defense against EBV infection. Thrilled to have contributed to this study with Cindy Ma Garvan Institute of Medical Research. Congrats!

Very happy to present our latest finding. Proud of our incredible team Radboudumc Human Genetics Nijmegen, Radboudumc and grateful to all collaborators! Cas van der Made Radboudumc_weet

Detecting Somatic Mutations Without Matched Normal Samples Using Long Reads buff.ly/4ci4qLS

This is a miracle that is built on decades of sustained, robust public investment in science. Not just applied work that directly led to these trials, but basic studies that told us how chloride channels and secretory pathways and lung cells work. It didn't come from nowhere.

😍 ' moment of the entry of Lipofectamines into the cell via endosome-rupture'

So many wonderful cell biology ideas behind how John Heuser captured these rare, transient, asynchronous moments. Read them here:

early #EM_Monday Hanieh Falahati هانيه فلاحتى
biorxiv.org/content/10.110…

🗓️ Join us on March 8, 2024, for a new #fridayseminar featuring Prof. Maria Rescigno from Humanitas University and Humanitas Research Hospital for an enlightening talk on the role of microbiota in the gut-liver-brain axis.🧠🧫🔬

Looking for an immunology postdoc in a fun lab studying inborn errors of immunity? Want to climb mountains literally and figuratively? Look no further! Come join Hsieh Lab! #thelabthatcookstogetherstaystogether

1/ Just in! We report the first humans with inherited pre-TCR⍺ deficiency in @sciencemagazine. Dive into our fascinating findings on complete and partial forms of pre-TCRα deficiencies, including a common variant in the Middle East and South Asia. science.org/doi/10.1126/sc…

🚨 IT'S RARE DISEASE DAY GLOBALLY! 🚨 Join us marking #RareDiseaseDay 2024! Spread awareness, share stories, and support those living with rare diseases. Together, we make a lasting impact! #ShareYourColours

A pile of papers waiting on the desk and then this 💥💥💥