The one and only Ravi A Madan M.D. giving a brilliant UW Health | Carbone Cancer Center Grand Rounds talk on re-thinking cancer immunotherapies! National Cancer Institute PCF Science Adam Sharp

Fragmentomic analysis of circulating tumor DNA targeted cancer panels. #BeyondTheAbstract with Kyle Helzer, Marina Sharifi, Jamie Sperger, Josh Lang, and Shuang Zhao UW–Madison > bit.ly/3upmGBD Annals of Oncology

Daniel G. Stover, MD, on Early-Stage Breast Cancer: A Biomarker Analysis From the PALLAS Trial ascopost.com/videos/2023-sa… #bcsm #breastcancer #oncology #SABCS23 SABCS Daniel Stover, MD, FASCO The James

Congratulations to the 2023 Bothwell Prize Winning paper from Zhao et al (with senior author Dr. Josh Lang, Department of Human Oncology)! #mcardlelab UW Health | Carbone Cancer Center mcardle.wisc.edu/2024/01/02/bot…

Noninvasive detection of NEPC by targeted cfDNA methylation Cancer Discovery co-led by Francesca Demichelis and her lab Università di Trento. Congrats to first author Gian Marco Franceschini 🇺🇦 and thank you to many amazing collaborators PCF Science Dana-Farber Lank Center for Genitourinary Oncology #NEMO aacrjournals.org/cancerdiscover…

ctDNA 'tumor fraction' is a simple concept & remains a relevant biomarker in diverse cancers. Broad Institute Genomics Platform & Daniel Stover, MD, FASCO validated shallow WGS assay sensitivity, precision, repeat-/reproducibility, & pre-analytic factors - in The Journal of Molecular Diagnostics jmdjournal.org/article/S1525-…

This is a critical need. Why is histologic subtype so rarely reported? Why so few subset analyses? Thanks to Christine Desmedt and colleagues for highlighting this! CC: Dr. Steffi Oesterreich Michał Sikora

Looking forward to visiting the University of Wisconsin, Madison, to deliver the grand rounds lecture and connect with collaborators. cancer.wisc.edu/research/event…

The PCF Young Investigator Forum at #PCFRetreat24 kicks off with a Panel: “Handbook for Starting a Lab” with Rohit Bose Claire E Fletcher Adam Sowalsky Asmaa E. (She/her) Andrew Goldstein & Goutam Chakraborty

Great way to start the #PCFRetreat24 with a Young Investigator day session with insights on leaving the postdoc nest to start your independent lab! Thank you Asmaa E. (She/her) Andrew Goldstein Goutam Chakraborty Claire E Fletcher Rohit Bose Adam Sowalsky for the advice and guidance on hiring &

PCF haiku!! Table 3 ftw #PCFRetreat24 Claire de la Calle Adam Sharp

BTCRC-BRE16-042 has been accepted as a poster presentation at SABCS 2024! This study is led by sponsor-investigator Nancy Chan, MD & co-investigator Coral Omene, MD, PhD. Congratulations to all co-authors and study teams involved in the study! Read more: bigtencrc.org/btcrc-bre16-04…

Great panel on case based discussion on ER positive #breastcancer! Daniel Stover, MD, FASCO presenting data on ctDNA & clinical utility in MBC! Ohio State Medical Oncology The James Dionisia Quiroga, DO, PhD, FASCO Hem-Onc Fellows Network SABCS William Gradishar, MD Neil Vasan #SABCS24

Proud to see research coordinator and med school candidate, Darian Louthan, present a BigTen CRC ph2 study with Marina Sharifi and Cristina Truica of continued ET + alpelisib in mPI3k MBC. University of Wisconsin Department of Medicine UW Health | Carbone Cancer Center

💔💔💔

Heartbroken💔we lost Dr. Felix Feng— close friend, selfless collaborator, brilliant scientist & a man who saved many prostate cancer lives with a triad of generosity, kindness, & teamwork. We miss you Felix Feng --too early my friend. To all: please consider supporting this

In TAILORx (LN- HR+) pts w/ RS≥31 addition of anthracycline results in benefit in 5-yr DRFI (5% HR 0.32) vs TC 📏benefit most clear in tumor >2 cm ↗️Increasing RS≥31 corresponded to increasing benefit of addition of anthracycline #SABCS24 SABCS OncoAlert

Important presentation on anthracyclines and outcomes in TAILORx by OncotypeDX score. Anthracycline chemo benefit over TC limited to T2 or larger tumors with ODX => 31. See also our recent Journal of Clinical Oncology editorial on this topic.

Thrilled to share a project that we envisioned over a decade ago to perform high purity/high specificity molecular analysis of circulating tumor cells! Led by the brilliant Marina Sharifi and Jamie Sperger AACR Funded by PCF Science NIH CDMRP

Check out our latest study! Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer | PNAS pnas.org/doi/10.1073/pn…