And here's another movie from our @MBoCjournal paper. This time the optogenetic oligomerization was triggered in interphase cells. molbiolcell.org/doi/10.1091/mb…

A celebration of the 25th anniversary of chromatin-mediated spindle assembly | Molecular Biology of the Cell molbiolcell.org/doi/full/10.10…

Spindle assembly in Xenopus egg extracts! Videos were taken while working late into the night at Marine Biological Laboratory (MBL) with Aaron Groen and Gatlin Lab Group. The montage is from our (Vikash Verma) recent retrospective in @MBoCjournal on a seminal paper by Rebecca Heald. ow.ly/GTsW50HHlPY

The Ndc80-Cdt1-Ska1 complex constitute a minimal processive kinetochore-microtubule coupling unit biorxiv.org/content/10.110…

Congrats to #UMass #Biology Assoc. Prof. & Dir. of the Molecular & Cellular Biology Program Tom Maresca Maresca Lab for being awarded a Fulbright Scholar Award! umass.science/3xZzSwx

Check out our new preprint: An intrinsically disordered kinetochore protein coordinates mechanical regulation of chromosome segregation by dynein biorxiv.org/content/10.110…

Very happy and proud to share the work PhD student Joana Lima i3S-Instituto de Investigação e Inovação em Saúde “A nuclear signal in prophase determines centrosome positioning and ensures efficient mitotic spindle assembly”, now online. biorxiv.org/content/10.110…

Check out the new Maresca Lab preprint (with Vikash Verma and Pat Wadsworth). Look at that dynein go! biorxiv.org/content/10.110…

McGory et al Maresca Lab UMass Amherst reveal that multimerization of the disordered #kinetochore protein Spc105 helps recruit a pool of the dynein-targeting RZZ complex to promote accurate chromosome segregation hubs.la/Q02frLw90 #CellDivision #Cytoskeleton #mitosis

Multimerization of a disordered #kinetochore protein promotes accurate chromosome segregation by localizing a core #dynein module, say Jessica McGory, Thomas Maresca Maresca Lab and colleagues UMass Amherst: hubs.la/Q02frL-d0 #Mitosis #CellDivision #Cytoskeleton

I am hiring in 2024. Contact me if you'd like to learn about my lab and the NIH

Image shows characterization of cytosolic Spc105 oligomers. McGory et al. Maresca Lab UMass Amherst uncover a linkage between the disordered kinetochore protein Spc105 and the dynein-targeting RZZ complex. hubs.la/Q02frJnM0 #Mitosis #CellDivision #Cytoskeleton

Magnetic Isolation and Concentration (MagIC)-cryo-EM is a new method to enable direct structural analysis of targets captured on nanomagnetic beads, which requires only 0.0005 mg/mL of targets in 100 µL crude solution to make 10 cryo-EM grids. I will explain the magic behind it!

Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes biorxiv.org/content/10.110…

Proximity-based activation of AURORA A by MPS1 potentiates error correction biorxiv.org/cgi/content/sh… #biorxiv_cellbio