Marcus Ruscetti Lab
@marcus_ruscetti
Ruscetti lab @UMassChan. Defining and targeting tumor intrinsic drivers of immune evasion for cancer immunotherapy. #prostatecancer #pancreaticcancer
ID: 977201474441793536
https://www.umassmed.edu/ruscettilab/ 23-03-2018 15:12:41
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Congrats to our talented former postdoc Lo and amazing research associate Kelly on their paper acceptance Science Translational Medicine! This was really a team effort from almost everyone in our lab and a great collaboration with Prabhani Atukorale. Stay tuned for the paper to drop next month!
I love Chaitanya Parikh's interdisciplinary and collaborative spirit! RNA Therapeutics Institute peeps come check out how Chaitanya is applying mRNA technology to cancer immunotherapeutics.
Very appreciative to the BRIDGE FUND UMass Chan Medical School for supporting our work and ongoing collaboration with Prabhani Atukorale to engineer multi-targeted LNPs for improved delivery of tumor and immune targeting therapies for pancreatic cancer!
Congrats Meng-Ju Wu and colleagues on this exciting study unveiling a new pathway by which IDH mutations lead to cGAS-STING suppression. Very impressive!
What a pleasure to have Morelia Morel Diaz join us as a SURP undergraduate student UMass Chan Medical School this Summer. She did a fantastic job and brought so much energy to the lab. It is such a pleasure having enthusiastic and gifted young scientists in the lab. The future is bright!
Excited to share our preprint on the role of mitochondrial calcium in pancreatic cancer plasticity & metastasis. In collaborative work with Jillian Weissenrieder in Kevin Foskett lab and Jessica Peura Nikita Calvin Johnson in my group, we show... 🧵 [1/7] biorxiv.org/content/10.110…
Join us! My lab UMass Chan Medical School is seeking postdocs and research associates who are passionate about how changes in metabolism and epigenetics contribute to cancer development and immune system evasion. DM me for a chat and apply at ummsjobs.com/job/10593/ (postdoc position)
Congrats Prabhani Atukorale Griffin Kane Meghan and Miranda!
Happy to see our joint effort with Anil K. Rustgi, Sims, and Chandwani labs come out this week where we took a deep dive into the role of FRA1 during acinar-to-ductal metaplasia (ADM). sciencedirect.com/science/articl…
Micronuclear collapse triggers chronic STING signaling that drives metastasis. But how do they rupture?? Beautiful work from the Samuel Bakhoum lab, led by brilliant physicist turned hard core cell biologist Melody Di Bona, explains how..
Innate immune activators packaged in lipid nanoparticles, and paired with two senescence-inducing chemotherapy agents, controlled tumor growth and extended survival in a mouse model of pancreatic ductal adenocarcinoma. Science Translational Medicine scim.ag/8eZ