Want to expand your #bioinformatics toolkit by including #RNAseq or #scRNAseq? CBW is offering a pair of consecutive workshops in Toronto this July that will teach you how to investigate the transcriptome. Take one or both! bioinformatics.ca/workshops/curr…

So...is MALAT1 even a real thing? (it's so consistently the top hit in any expression analysis, I'm curious if any studies actually isolate its functionality rather than its pervasive correlation with *everything*)

Sharing this exciting opportunity for a colleague. careers.ucalgary.ca/jobs/14165302-…

Another opportunity that crossed my desk: external-nationwidechildrens.icims.com/jobs/49731/igm… These folks are doing really cool stuff.

A single-cell TCR-seq method for dogs suggests reannotation of some non-functional VJ genes and differentiates between diverse repertoires of healthy dogs and expanded repertoires in malignancies: nature.com/articles/s4200… Obi Griffith, PhD @WUDeptMedicine Malachi Griffith

I am delighted to announce that I will be opening my lab on July 1 at Washington University in St Louis within the Division of Oncology, Department of Medicine, & Section of Computational Biology! @WUDeptMedicine @WashUFWIM 1/4

If you are interested in this work, please consider applying here: wustl.wd1.myworkdayjobs.com/External?q=Fol… ! 4/4

What's the fastest antigen-specific TCR discovery method that's practical (publicly available validated kit, <$5k per antigen, arbitrary HLA alleles)? What's better than just doing peptide+PBMC culture followed by 5'GEX+VDJ scRNA-seq?

Anyone savvy CS x immunology x genomics looking for computational work?

Applications are open for the Advanced Sequencing Technologies & Bioinformatics Analysis course Cold Spring Harbor Laboratory. This intense 2wk course will immerse you in genomics technologies and teach you the fundamental computational skills you need to analyze your own data. meetings.cshl.edu/courses.aspx?c…

Our featured GCBR of the Week is CIViC, a community driven resource that improves the clinical interpretation of genetic variants in cancer. Click the link to find out more : bit.ly/4dqfpCO National Human Genome Research Institute #globalbiodata #openscience

TCR constant region not exactly constant: "For TRBC1, ...83%...contained TRBC1∗03, 2 carried (11%) TRBC1∗01, and only a single haplotype carried TRBC1∗02. Lastly, for TRBC2, we identified 6 alleles, including 4 novel alleles..." cell.com/cell-genomics/…

Excited to announce Splam is now published in Genome Biology! Splam, trained on thousands of splice junctions from GTEx, is your go-to tool for scoring splice junctions from alignment or annotation files. Mihaela Pertea Steven Salzberg 💙💛 Alan Mao doi.org/10.1186/s13059…