Our new preprint is out on #cancer #plasma #biomarker #proteomics "Biomarker Candidates for Tumors Identified from Deep-Profiled Plasma Stem Predominantly from the Low Abundant Area" biorxiv.org/content/10.110…

Proteomics should be sensitive, accurate, fast, robust & affordable. 👉 Welcome plexDIA! Proteins / sample: ~ 8,000 Sample size: 500 ng Samples / day: 48 (should be 72 with Evosep) MS system: 1st generation QE classic biorxiv.org/content/10.110…

3 gute Nachrichten zu omikron (ja, es gibt sie!): 1) es ist leicht festzustellen 2) Antigentests schlagen darauf an 3) wir dürfen auf weiter guten Schutz durch Impfung vor schwerer Erkrankung(!) hoffen. Alle drei haben eine Sache gemeinsam … 🧵

Forschende der ETH Zürich entwickelten eine neue Methode, mit der sie messen können, wie #Proteine auf der Oberfläche von #Zellen organisiert sind. Die Erkenntnisse könnten unter anderem zur Entwicklung neuartiger #Krebsmedikamente führen. Bernd Wollscheid ethz.ch/de/news-und-ve…

Scientists at ETH Zurich have developed a new method to determine how #proteins are organised on the surface of #cells. Insights gained with the technology could lead to the development of novel #drugs to fight #cancer. Bernd Wollscheid ethz.ch/en/news-and-ev…

Meet the neighbors! Context-dependent interactions within protein communities enable cells to adapt to diverse environments. Dysfunctional protein communities drive disease. LUX-MS platform permits spatially-resolved #surfaceome analysis. Distance matters rdcu.be/cCtzJ

Happy to contribute to this work led by Bernd Wollscheid lab on optoproteomic LUX-MS technology to decode ligand receptor interactions. #MSFragger open modification search helped to reveal light-induced protein labeling sites and then to optimize the subsequent MS data analysis.

An optoproteomic method from Maik Müller, Bernd Wollscheid and coworkers enables mapping of protein interactions on the cell surface, revealing cellular responses to antibodies, drugs and viral particles as well as immunosynapse signaling events ETH Zurich go.nature.com/3rHZBXr

Happy to share our latest paper about the constitutive biogenesis of the MHC class I immunopeptidome across primary tissues! HUPO-HIPP Human Proteome Cell Press sciencedirect.com/science/articl…

Our paper on #DUBTACs for targeted protein stabilization is now out in Nature Chemical Biology! Congrats & thanks to Nathaniel Henning, Lydia Boike, PhD of College of Chemistry and many folks in our lab & Novartis Science that made this possible! Also thanks to The Mark Foundation for Cancer Research! 1/n nature.com/articles/s4158…

Excited to announce extension of our alliance between UC Berkeley & Novartis Science w/the Novartis-Berkeley Translational Chemical Biology Institute to include @dannomura, Toste Group, Tom Maimone, @olzmannlab, & Ziyang Zhang to tackle the "undruggable"! businesswire.com/news/home/2022…

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

"It was always my hope that, as a scientist, I could make some contributions that would benefit human health." Listen to our conversation with 2022 chemistry laureate Carolyn Bertozzi, where she shares why she wanted to become a scientist and the importance of chemistry:

We looked at the proteomic diversity of 18 different synapse-types! Check out what we found in the preprint below 👇Big thanks to my co-authors from Erin schuman lab at MPI for Brain Research and Swiss National Science Foundation for support. #TeamMassSpec biorxiv.org/content/10.110…