Over 1,000 responses in 4 days from 55 countries so far!🔥🔥👏👏👏 Have your say on how we manage S aureus bacteremia: redcap.duke.edu/redcap/surveys… @VanceFowler5 Let's see if we can get to 2000 responses and have a globally representative dataset!

Magphi is v2.0.0! (github.com/milnus/Magphi) What it new? 1. Andrew has implemented tblastn, allowing amino acid seeds as input! 2. fasta and Gff outputs will by default be oriented to have the same strand and start site, for easier passing to alignment tools.

Please RT - if you're into pathogen genomics then check out this postdoc opportunity on a collaborative project with our team and @ESRNewZealand on #StrepA Three years for now, but an option for permanent upon successful completion 🧬🧫

We are excited to share the preprint behind mge-cluster, our new pipeline to cluster plasmid sequences Dr. Rebecca Gladstone J_Gamma Anita Schürch Val F. Lanza @Orjan_Samuelsen @Paal_Johnsen

We've been working on an update to the ska tool, which uses 'split k-mers' to align closely related populations of pathogens. It's just had it's first release and we'd welcome any testing or feedback github.com/bacpop/ska.rust

Our team's latest work published in Nature Reviews Microbiology. Here we cover the most recent advances and developments in Group A Streptococcal research nature.com/articles/s4157… Well done Stephan Brouwer, Tania Rivera H Mark_Davies_Lab & team! #GroupAStrep

Looking for a software engineer to join me and the talented team at AusTrakka - Australia's national pathogen genomics surveillance system. Based in Melbourne, Australia at Doherty Institute @ University of Melbourne . 🇦🇺🦠🧫🧬🖥️ 🌴 jobs.unimelb.edu.au/en/job/912211/…

Very excited our paper is out today in The Lancet Microbe 🦠🧬📜 This was an amazing inter-disciplinary project where we found asymptomatic throat carriage of Strep A is a likely source of skin infections in remote tropical settings #StrepA #RHD #GAS #ARF doi.org/10.1016/S2666-…

Is it time for a platform trial for invasive B-hemolytic streptococcal infections? authors.elsevier.com/a/1hGR5,RGPgSB… This survey led by Ravi Dotel suggests yes. Joshua Davis Asha Bowen Ouli Xie Jonathan Carapetis Clinical Microbiology and Infection

🚨 Want to fit a molecular clock, or 2? 🚨 👉 Try clockor2.github.io - a client side tool for fitting global and local clocks with root-to-tip regression. Developed in collaboration with Wytamma, arambaut, and Sebastian Duchene (rb.gy/dro6j)

Our work to find that the throat is an important reservoir for Strep A in areas with endemic skin infections. Interventions to reduce spread likely need to consider the throat. Full paper here: thelancet.com/journals/lanmi… And Guardian piece: theguardian.com/australia-news…

Can we use bacterial GWAS to inform treatment choices in in Staphylococcus aureus sepsis ? In our paper just published in Cell Reports we delve into bacterial heritability, lineage effects and adaptive mutations behind infection outcomes. Link here: 10.1016/j.celrep.2023.113069

Great to share our latest paper in Nature Communications examining real-world transmission interactions between S. pyogenes and the emerging pathogen S. dysgalactiae subp. equisimilis (SDSE) doi.org/10.1038/s41467… Steven Tong Mark_Davies_Lab Doherty Institute + many collaborators! 🧵👇

We have a research position in 'Microbial Bioinformatics' available in our laboratory. Masters/PhD level applicants with bacterial genomics experience are encouraged to apply. Come and join us Doherty Institute UniMelb MDHS! Applications close 17 June 2024 jobs.unimelb.edu.au/caw/en/job/916…

With an ageing population, we should be wary of the clinical burden of pathogens such as SDSE. Timely review led by the talented Ouli Xie. More clinical information on SDSE disease is needed (watch this space....)

Out now: Magnus Jespersen latest PhD work: journals.asm.org/doi/10.1128/sp… Systematic evaluation of existing #StrepA transposon mutagenesis work using a pan-genome framework. Interactive html is included for searching of your favour strepA gene: zenodo.org/records/107962… Andrew Steven Tong

🏆 Huge congrats to Mark_Davies_Lab from Doherty Institute who, together w/ collaborators at Institute for Molecular Bioscience, won the prestigious #EurekaPrize for their crucial work on tracking Strep A spread and advancing vaccine development. [Watch youtu.be/bIqXK4VfFMI] UniMelb MDHS University of Melbourne The Royal Melbourne Hospital