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Congratulations to the MacMillan Group on their paper out today in nature: “Alkene dialkylation by triple radical sorting.” Well done Johnny, Will, and Dave! Story here: bit.ly/49vA4n6

Interested in converting an aliphatic alcohol directly into its bioisostere? Check out our method for deoxydifluoromethylation of alcohols. Congrats to Edna, Nico Cesar Nicolas, and Holt Sakai! Read the full paper out now in J. Am. Chem. Soc.. pubs.acs.org/doi/10.1021/ja…

Check out our work on alkene dialkylation by sorting not one, not two, but THREE radicals! Great work Johnny and Will! nature.com/articles/s4158…

🔬 Celebrating the brilliance of women in the MacMillan lab this #InternationalWomensDay! Our female scientists inspire excellence every day. 💪🧪 #WomenInSTEM #ChemistryWonders #IWD2024

Check out our recent paper where we take diols and bromoalcohols to form strained bicyclic, fused, and spirocyclic compounds through a new concept, couple-close. Big thanks to our collaborators at Janssen Pharmaceuticals at Spring House! nature.com/articles/s4158…

A light-driven reaction sequence that bolts nonaromatic rings onto heteroarenes, such as pyridines, offers a rapid route to medicinal molecules that would be troublesome to make using existing methods: cen.acs.org/synthesis/Phot…

17 years in the making.. We are super excited to finally achieve alcohol-alcohol cross-coupling enabled by the powerful SH2 radical sorting! Great work Jerry, Nick, Jay, James, Colin and Robert. Big shout out to our collaborator Jesus from Janssen Spain. science.org/doi/full/10.11…

“People are suggesting scientists are elitist. This is exactly the opposite of what science is. Scientists are doing everything for the community. They are not sitting at the top of the mountain they are sitting at the bottom trying to make sure everyone can get to the top of the

Congratulations to MacMillan Group postdoc Steve Knutson for being awarded a K99/R00 NIH NIGMS Pathway to Independence Award to develop new proximity labeling tools for RNA biology! Well done, Steve!

Online now! #Review Current advances in photocatalytic proximity labeling by Steve Knutson, David W.C. MacMillan MacMillan Group, and colleagues at Princeton Chemistry Princeton University dlvr.it/T5yB46 #chembiol

Check out our latest work in JACS where a high energy radical and primary radical are generated in the presence of unactivated alkenes and sorted toward aryl-alkylation. Congrats Johnny, Edna, Jennifer, and Will!  pubs.acs.org/doi/10.1021/ja…

Triple Radical Sorting: Aryl-Alkylation of Alkenes J. Am. Chem. Soc. #Chemistry #Chemed #Science #TechnologyNews #news #technology #AcademicTwitter #ResearchPapers pubs.acs.org/doi/10.1021/ja…

Free-Radical Deoxygenative Amination of Alcohols via Copper Metallaphotoredox Catalysis J. Am. Chem. Soc. #Chemistry #Chemed #Science #TechnologyNews #news #technology #AcademicTwitter #ResearchPapers pubs.acs.org/doi/10.1021/ja…

Free-Radical Deoxygenative Amination of Alcohols via Copper Metallaphotoredox Catalysis | JACS MacMillan Group Princeton Chemistry Princeton University Total Synthesis and Methodology Highlights #Radical #Deoxygenative #Amination #Alcohols #Cu #Metallophotoredox #Catalysis pubs.acs.org/doi/10.1021/ja…

Interested in forging carbon—nitrogen bonds? Merging photoredox and copper catalysis platforms, we can now make these bonds from alcohols. Now out in JACS! pubs.acs.org/doi/10.1021/ja…

Congratulations to the MacMillan Group for their latest, just out in nature: “Unlocking carbene reactivity by metallaphotoredox a-elimination.” Great work by Ben, Nathan, Dave and colleagues at Janssen: bit.ly/4ebrtsH

For any cyclopropane fans – ICYMI, see our latest report in nature. Using one-electron logic, iron carbenes can be made from simple reagents like lactic acid, trifluoroethanol or alanine. Congrats to Ben, Nate and our awesome collaborators at Janssen! nature.com/articles/s4158…

Congratulations to our German postdoc Johannes Grosskopf (Johannes Großkopf) who has been awarded the 2024 Albert-Weller award by the German Chemical Society GDCh Division of Photochemistry for his outstanding contributions to photochemistry as a young academic. Well done, Johannes!

Farewell, Vittorio and Ryan! It's been a pleasure having you both in the lab, sharing your knowledge and passion for chemistry. Wishing you all the best in your next adventure. You'll be missed! #SafeTravels

Check out our latest article in Nature Chemical Biology where an intracellular micromap proximity labeling platform is established to investigate stress granule disassembly mechanisms. Congrats to Roderick, Steve and Sean! nature.com/articles/s4158…