Shannon Macauley
@macauleylab
Associate Prof, PhD, wife, mom. Alzheimer’s disease | diabetes | brain metabolism | sleep | I ❤️ lactate | lysosomal storage diseases | she/her
ID:1026986793059721218
http://www.macauleylab.com 08-08-2018 00:21:46
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I am thrilled to share our lab's latest work documenting sex-differences (SD) in P2RY12's regulation of microglial morphology, synapse density and locomotory behavior. This work is our lab's first dive (of hopefully many)into microglial SD led by Uweru Joseph jneuroinflammation.biomedcentral.com/articles/10.11…
Check out what Rejane Rua and I wrote about BAMs’ roles, their changes during brain infections, and how these very special macs might play key role(s) in neurodegenerative diseases. It is “borderline” controversial 😁😉😂💪🏻
Wonderful time presenting at #ASN2024 with this fantastic group. Thanks to Danielle Beckman Chen Wenqiang and Dr. Elizabeth Rhea for a great session on glia, metabolism, and Alzheimer's disease! Great science, great food, and great company!
#WeekendRead ! #EveryCellIsAnImmuneCell ! Raghavan &co show The EMBO Journal that in #skin epidermis ROS drives glycolysis & lactate! Lactate uptake by macrophages boosts their TCA cycle & matrix remodeling via MPP9 to drive #sterile #inflammation & #psoriasis ! doi.org/10.1038/s44318…
New work from by Jennifer Lawrence from Erik Musiek Lab !
Microglia drive diurnal variation in susceptibility to inflammatory BBB breakdown
Is anyone going to AmSocietyNeurochem? 🤓
We will be presenting in a cool section Tues afternoon! Come discuss brain metabolism in Alzheimer's disease with me, Shannon Macauley, Chen Wenqiang, and Dr. Elizabeth Rhea at 🧠 #ASN2024 .
My first time going to Portland! What I can't miss? :)
What Is the Role of Lactate in Brain Metabolism, Plasticity, and Neurodegeneration? bit.ly/3JeSIo0
#NeuroTwitter #Neurology
interested in microglia functional genomics?
check out the newest paper from the Sher lab
Dr. Falak Sher
sherlab.org
stemcellres.biomedcentral.com/articles/10.11…
MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation #NucleicAcidsRes academic.oup.com/nar/article/do…