Marianne Chapleau (@m_chapleau) 's Twitter Profile
Marianne Chapleau

@m_chapleau

Neuropsychologist turned Medical Science Liaison. Passionate about patient care & improving the diagnosis of neurodegenerative diseases. Views are my own.

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calendar_today28-01-2020 19:27:13

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Marianne Chapleau (@m_chapleau) 's Twitter Profile Photo

When I was interviewing for roles in industry, someone asked what I enjoy doing, and I said "going to conferences" (😂). She laughed and said that few jobs in pharma offer that opportunity. If you love discussing science & networking, the MSL role may be perfect for you! #AAIC24

When I was interviewing for roles in industry, someone asked what I enjoy doing, and I said "going to conferences" (😂). She laughed and said that few jobs in pharma offer that opportunity. If you love discussing science & networking, the MSL role may be perfect for you! #AAIC24
The Lancet (@thelancet) 's Twitter Profile Photo

Current projections estimate 153 million people will be living with dementia by 2050. Nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors starting in childhood, suggests new report from a standing Lancet Commission: buff.ly/46nvoPR

Current projections estimate 153 million people will be living with dementia by 2050. 

Nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors starting in childhood, suggests new report from a standing Lancet Commission: buff.ly/46nvoPR
Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Very happy to share our new work out in Alzheimer's & Dementia Journals, showing that combining PI-2620 tau-PET and fluid p-tau markers can help discriminate 4R tauopathies vs. AD. Huge thanks to first author Roxane Dilcher and co-senior MatthiasBrendel doi.org/10.1002/alz.14…

Very happy to share our new work out in <a href="/alzdemjournals/">Alzheimer's & Dementia Journals</a>, showing that combining PI-2620 tau-PET and fluid p-tau markers can help discriminate 4R tauopathies vs. AD. Huge thanks to first author <a href="/dilcher_r/">Roxane Dilcher</a> and co-senior  <a href="/matbrendel/">MatthiasBrendel</a> 

doi.org/10.1002/alz.14…
RikOssenkoppele (@rikossenkoppele) 's Twitter Profile Photo

Lewy body pathology exacerbates brain hypo-metabolism and cognitive decline in Alzheimer’s disease Great work led by Lyduine Collij. Using ADNI data, she showed that the presence of LB pathology (CSF SAA) exacerbates global cognitive decline in symptomatic AD and is associated with

Lewy body pathology exacerbates brain hypo-metabolism and cognitive decline in Alzheimer’s disease

Great work led by <a href="/LECollij/">Lyduine Collij</a>. Using ADNI data, she showed that the presence of LB pathology (CSF SAA) exacerbates global cognitive decline in symptomatic AD and is associated with
Marianne Chapleau (@m_chapleau) 's Twitter Profile Photo

Someone just sent me this gem from a conference… Check out Figure 1 — yep, straight from our lit review in JNM! No citation, no credit… 😂🤯 Trainees, this is your friendly reminder: always cite your sources, or else you might end up on someone’s Twitter! 😉

Someone just sent me this gem from a conference… Check out Figure 1 — yep, straight from our lit review in <a href="/JournalofNucMed/">JNM</a>! No citation, no credit… 😂🤯 Trainees, this is your friendly reminder: always cite your sources, or else you might end up on someone’s Twitter! 😉
Marianne Chapleau (@m_chapleau) 's Twitter Profile Photo

Well said! And this framework does not diminish the importance of syndromic diagnosis or the quantification of clinical impairment.

Maria C Carrillo PhD (@drmariaalz) 's Twitter Profile Photo

Join us at #AAICAdvancements Exploring Equity in Diagnosis, Nov. 18-19 in Chicago and online! Be a part of the conversation around addressing disparities in an era of modernizing diagnosis for Alzheimer’s and other dementias. #ExploringEquity24 alz.org/exploringequity

Jake Vogel (@_jakevogel_) 's Twitter Profile Photo

Whelp. Maybe a good time to mention that I am about to open a new PhD position in Sweden that just happens to be exactly four years in length. Any aspiring PhD candidates in neurodegenerative imaging or multiomics who want to "take a break" from the US, please get in touch!

Sara Nolin, PhD 🧠 (@saranolin_neuro) 's Twitter Profile Photo

📢 Looking for a postdoc opportunity in neuroimaging research! 🎓 My focus: Alzheimer’s disease, cognitive aging, & functional networks. Skilled in multiple MRI modalities and neuropsych. Excited to connect with labs! #Postdoc #AlzheimersResearch #Neuroimaging

JAMA Neurology (@jamaneuro) 's Twitter Profile Photo

Study found frailty accelerates up to 9 years before dementia onset and is a key early marker. Frailty was linked to higher dementia risk even when measured years before dementia onset and may represent a target for prevention efforts. ja.ma/4hLFake

Study found frailty accelerates up to 9 years before dementia onset and is a key early marker. Frailty was linked to higher dementia risk even when measured years before dementia onset and may represent a target for prevention efforts. 

ja.ma/4hLFake
CurePSP (@curepsp) 's Twitter Profile Photo

#CurePSP is now accepting applications for the Student Fellowship Program. This program supports students engaged in research on PSP and CBD, providing resources to drive meaningful advances in the field. Deadline: January 31, 2025, by 5pm ET psp.org/iwanttolearn/s… #Research

#CurePSP is now accepting applications for the Student Fellowship Program. This program supports students engaged in research on PSP and CBD, providing resources to drive meaningful advances in the field. 

Deadline: January 31, 2025, by 5pm ET
 psp.org/iwanttolearn/s…

#Research
Marianne Chapleau (@m_chapleau) 's Twitter Profile Photo

Exciting news for Alzheimer’s treatment in Europe! National decisions on access, pricing, and reimbursement are next, but this is a big step forward! 🎉

JAMA Neurology (@jamaneuro) 's Twitter Profile Photo

ARIA-E in Alzheimer disease is more likely in those with APOE ε4, microhemorrhages, low CSF Aβ42, and high Fazekas scores, but it does not generally worsen long-term cognition or function. ja.ma/4fOVui3

ARIA-E in Alzheimer disease is more likely in those with APOE ε4, microhemorrhages, low CSF Aβ42, and high Fazekas scores, but it does not generally worsen long-term cognition or function. ja.ma/4fOVui3
Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Massive paper alert: We performed extensive profiling of PI-2620 for 4R tauopathies. PI-2620 tau PET signals in PSP stem from neuronal and oligodendroglial tau, not astrocytes. Signals correlate with fibrillary tau, autoradiography, and autopsy data in PSP doi.org/10.1007/s00401…

Anna Marseglia (@anna_marseglia_) 's Twitter Profile Photo

📣 Postdoc Hiring📣 Join our project on how social health impacts cognition & resilience with a focus on women’s health ✅ Longitudinal data expertise  ✅ Passion for aging research ✅ Team-oriented mindset 📍Karolinska Institutet 🇸🇪 💼 Apply now: ki.varbi.com/en/what:job/jo…

Marianne Chapleau (@m_chapleau) 's Twitter Profile Photo

Happy to share this great review on florbetaben, led by Aleksandar Jovalekic, highlighting its pivotal role in imaging Alzheimer’s pathology since its approval 10 years ago. Grateful to have collaborated on this work! mdpi.com/1424-8247/17/1…

RikOssenkoppele (@rikossenkoppele) 's Twitter Profile Photo

🚨NEW PREPRINT: An atypical phenotype is a risk factor for higher mortality in Alzheimer’s disease Ilse Bader shows that an atypical (non-amnestic-predominant) clinical presentation is an important risk factor for mortality beyond age, sex, education, APOEε4-carriership and

🚨NEW PREPRINT: An atypical phenotype is a risk factor for higher mortality in Alzheimer’s disease

<a href="/ilse_bader/">Ilse Bader</a> shows that an atypical (non-amnestic-predominant) clinical presentation is an important risk factor for mortality beyond age, sex, education, APOEε4-carriership and
Marianne Chapleau (@m_chapleau) 's Twitter Profile Photo

Our team is hiring three MSLs! Check out our LinkedIn job posts. Perfect role for a neuropsychologist or neuroscientist specialized in AD who wants to transition to industry.