Great to see our organoid-microbe co-culture approaches published in Nature Protocols! Not just because they are the basis for several cool projects but also bc the author list reflects the many The Clevers Lab members who developed these in the past years. nature.com/articles/s4159…

#HumanProteinAtlas- Single Cell Type Atlas proteinatlas.org/humanproteome/… Search my genes across 192 cell types & 13 human tissues😀 Thanks! +wait for brain, skeletal muscle, bone & more organs🤠 Dr. Mathias Uhlén & Cecilia Lindskog labs Science Advances 2021 advances.sciencemag.org/content/7/31/e…

Genomics Integration into Nephrology Practice sciencedirect.com/science/articl…

Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs nejm.org/doi/full/10.10…

this is the way👍

Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children #MIS-C #TBX21 nature.com/articles/s4146…

CRRT effluent from pt in burn unit treated w/ CYANOKIT. Cyanide + hydroxocobalamin ➡️➡️ cyanocobalamin = reddish body fluids and dialysate. Ref: journals.sagepub.com/doi/full/10.11…

Rodent models of diabetic kidney disease: human translatability and preclinical validity #DKD

Insulin-derived amyloidosis in a type 1 diabetes patient. First time I see this type of amyloidosis 😳 A cause of poor glycemic control due to the impairment of insulin absorption. Anti-insulin immunolabelling can help to type amyloid deposits. #pathology #amyloidosis #diabetes

SGLT2 inhibition reduces the risk of serious hyperkalemia in people with diabetic kidney disease, which may enable greater use of RAAS inhibitors in CKD and/or heart failure New CREDENCE data presented this week at #ESCCongress, now in European Society of Cardiology Journals: academic.oup.com/eurheartj/adva…

Vagus nerve stimulation activates two distinct neuroimmune circuits converging in the spleen to protect mice from kidney injury | ⁦PNASNews⁩ ⁦UVA Nephrology⁩ Okusa team pnas.org/content/118/12…

my top ten list of drugs causing encephalopathy in ESRD: 1. gabapentin 2. baclofen 3. gabapentin 4.baclofen 5. gabapentin 6. baclofen 7.gabapentin 8. baclofen and don't forget #9 & 10: 9. neurontin 10. lioresal

🚨⭐️Snapshot: Trial Types in Precision Medicine Cell OncoAlert

In FIGARO-DKD, UACR ranging from 30 to < 300 and an eGFR of 25 to 90 The frequency of AE did not differ between the 2 groups . HyperK-related discontinuation of the study drug in the finerenone group (1.2%) than the placebo group (0.4%) #ESCCongress

Unconventional T cells and kidney disease ow.ly/ZCa750FZZlr Nature Reviews Nephrology

Outcomes of Nephropathic #Cystinosis doi.org/10.1016/j.kint… Bambino Gesù #cysteamine

#SSaSS at #ESCCongress In a #pragmatic (n=20,995) randomized trial, salt substitute (vs. regular): ⬇️stroke, MACE & ☠️ ✅No evidence of harm, incl. hypErK Interesting findings for a low-cost interv. Large-scale implementation challenging European Society of Cardiology NEJM nejm.org/doi/full/10.10…

#ESCCongress The SSAs study: What are the effects of salt substitutes in stroke, MACE, total mortality and hyperkalemia? Very important conclusions, all outcomes significantly reduced and no signs of hyperkalemia. Wonder what the effect would be in blacks! Dr Anastasia Mihailidou FAHA FCSANZ FESC

Hello, I'm currently looking for a Research Assistant (RA) position after my graduation in May 2022. My plan after doing RA is to go to PhD program in Biology. I attached a list of the techniques I have gained so far for your references. Thank you so much. Hiro. H