🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

The Holy Grail of Biology? 🧬 In this video podcast, Eric Topol talks with Head of Science Stephen Quake & EPFL’s Charlotte Bunne about their groundbreaking Cell paper + how AI could make biology 90% computational, 10% experimental. Watch now: bit.ly/3FMXxq6

behind the bars... #cryoem experts, what could be these bars?

TWiV reviews new committee of experts to counter vaccine misinformation, resignation of NSF Director, dependence of immune response to rabies virus on the gut microbiome, and a nucleosome switch primes hepatitis B virus infection. 📺 bit.ly/3EsZtEd

Our #RNA multimer paper out now in @nature! #cryoEM of 2 distinct nanocages GOLLD and ROOL and membrane-associated OLE. Multimers at ultra-low concentrations, special covariance for cross-molecule kissing loops, and speculation on function nature.com/articles/s4158…. 1/2

You want to start tomography? Solve structures inside cells? Reach Nyquist😳? We have a website for you! tomoguide.github.io You'll find a tutorial on how to reconstruct tomograms, pick particles and do subtomo averaging, using different software! Hope it will be useful !

Curve the way for the RNA virus replication complex to work. #Chikungunya #virus "Saddle Curvature Association of nsP1 Facilitates the Replication Complex Assembly of Chikungunya Virus in Cells" biorxiv.org/content/10.110…

How to find fantastic new #RNAs? The J2 antibody is the gold standard to detect, map & enrich dsRNAs. Co-led by Bou-Nader lab, Kevin Juma, Ankur Bothra & Steve Leppla’s lab, we visualize how J2 recognizes dsRNA and define its epitope, specificity & bias. doi.org/10.1101/2025.0….

If you are interested in microbiome, metabolomics, aging and precision medicine, this is a great opportunity to do postdoctoral training in Singapore!

...and big thanks to Janet Iwasa for making this amazing video to illustrate the strand-sliding mechanism!

Complete 5-methylcytidine substitution enhances the efficacy of self-amplifying RNA go.nature.com/3RYbPHK rdcu.be/em3ZT

Please register for the upcoming EXCEL Research Seminar on 13 June here: forms.office.com/Pages/Response…

The ChimeraX 1.10 release candidate and daily builds can predict small complexes of proteins, nucleic acids and small molecules using Boltz on your Mac, Windows or Linux computer. rbvi.ucsf.edu/chimerax/data/…

NTU Singapore invites applications for the prestigious Lee Wee Nam Professorship in Life Sciences, with a focus on Plant Science. Lead interdisciplinary research and shape the future of plant biology! 🌿🍀🌻🌴#PlantScience #AcademicJobs ntu.wd3.myworkdayjobs.com/Careers/job/NT…

Genetics of dengue epidemics - A review of how even a few genetic changes in the dengue virus genome can have major impact on virus transmission and outbreaks. Allyson Choi Duke-NUS Medical School sciencedirect.com/science/articl…

New story - the structure of the Vault cap at 2.3 Å! Fantastic work by Huan Li (Huan Li). For more details, read the preprint, or check out my thread at the other place! 😊🟦☁️ biorxiv.org/content/10.110…

This startup just dropped an AI model that will save many many lives. Chai-2 takes stubborn proteins and gives you a verified binder in 2wks, instead of 6-18mos. Its 16% hit rate is 100x better than previous methods! Medicine development is about to get way cheaper and faster.

New online! Structural basis for the synergistic assembly of the snRNA export complex bit.ly/44fJ1RP

How to build a thriving open source community by writing code like bacteria do 🦠. Bacterial code (genomes) are: - small (each line of code costs energy) - modular (organized into groups of swappable operons) - self-contained (easily "copy paste-able" via horizontal gene

Out Now! Amino acid changes in two viral proteins drive attenuation of the yellow fever 17D vaccine bit.ly/4eFeuQH #YellowFever #VaccineResearch #Virology

I saw it firsthand at the #Lindau2025 Nobel Laureates meeting--international young scientists welcomed and recruited in Germany and elsewhere. Some of the very best are leaving, and many of the best will no longer come. wsj.com/politics/polic…