Really cool to see this work out on minimal Ti plasmids to better understand Agrobacterium-mediated transformation of plants and fungi.

➡️ Enjoy this short piece with Vincent Courdavault highlighting the pionnering acheivements by the Keasling Lab 🏳️‍🌈🏳️‍⚧️ on metabolic engineering of plant medicines 🌿💊 nature.com/articles/s4157… Nature Reviews Genetics BBV Lab Université d'Angers Recherche et Innovation – Université d’Angers​ CHU Angers @FacSante_Angers SFR ICAT

@jdiggans @thesteinegger @hendrik_dietz Only reason I see for authors to use biosecurity as an excuse to limit access to source code/weights is to gain advantage over their competition.

Our work, led by former postdoc Yuzhong Liu and Professor Jay Keasling, on the complete biosynthesis of QS-21 in engineered yeast is out now in nature. We report the sustainable supply chain of an essential adjuvant for global immunization here: nature.com/articles/s4158…

The Hill-Maini lab website is live Stanford Bioengineering Stanford University. We are hiring for multiple postdocs who are excited about synbio/food/sustainability in filamentous fungi and building an inclusive and lab culture that fosters creativity! Spread the word!!! hillmainilab.com

The Keasling Lab at UC Berkeley/LBNL is looking for motivated undergraduate students interested in applying machine learning in metabolic engineering and fungal/plant synthetic biology. Apply here: 👇

Binary vector copy number engineering improves Agrobacterium-mediated transformation go.nature.com/3CdewQS

I am pleased to announce new research from the Shih Lab (ShihLab) published today in Nature Biotechnology on improving Agrobacterium-mediated transformation via binary vector copy number engineering (doi.org/10.1038/s41587…). 🧵A summary thread below🌿

New research shows that some simple changes to Agrobacterium can significantly improve the efficiency of introducing DNA into a genome, also known as “transformation.” @JBEI Institute for Geographic Information Science newscenter.lbl.gov/2024/11/07/new…

Excited to share our new CRAGE-based method for studying root-colonizing bacteria🌱🦠 This approach enabled us to profile thousands of promoter activities in Pseudomonas simiae during Arabidopsis root colonization, overcoming plant RNA interference. biorxiv.org/content/10.110…

Happy to share our new publication out today in Nature Plants where we quantitatively dissect synergy and antagonism that occurs during Nicotiana benthamiana transient agroinfiltration. Congrats to Simon, Matthew, Mitch and all other co-authors! nature.com/articles/s4147…

New OA Article: "Quantitative dissection of Agrobacterium T-DNA expression in single plant cells reveals density-dependent synergy and antagonism" rdcu.be/elJ5z News & Views: "Cooperation and antagonism in Agrobacterium-mediated transformation" rdcu.be/elJ5F

Check out our new preprint! We examined sources of variability of transgene expression in N. benthamiana agroinfiltration and ways to minimize it. Graduate student Sophia Tang observed FP expression in >1,800 plants over the course of nearly 3 years! biorxiv.org/content/10.110…

Antibiotic resistance is a major global threat. New therapeutic approaches will be vital to stem the tide of multidrug resistant bacterial pathogens. In the paper that we just released on BioRX (tinyurl.com/ytszdbxt), we introduce a new class of precision antimicrobials.