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News from the Rosetta community: Prosculpt – an open-source library integrating RFDiffusion, ProteinMPNN, AlphaFold2 & Rosetta into one easy workflow More via Ajasja 💻🧬🔬: rosettacommons.org/2025/05/28/all…

Advancing Drug Discovery with Rosetta Pocket Protocols and Boltz-2: Finding and Modeling Druggable Binding Sites levitate.bio/boltz/ai/ml/ro…

Great idea. We are trying to fill some gaps openfold but nowhere near enough resources to do so everywhere

Amazing data analysis. Seattle and the US are just a tiny microcosm of the under building in all ex UK colonies

From David Baker's lab, design of binders to intrinsically disordered proteins (IDP), with a very high success rate, 49/43 with only two dozen tested per target. Easier than for structured proteins now?? science.org/doi/10.1126/sc…

Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social Hi Roland. 👋

Congrats Elizabeth Wood 🧬🖥️🥼 I'm excited to see where this technology goes!

I'll be doing a (virtual) talk for BIO Asia about Cyrus's internal MHC II data platform HIDES and #ai model HIDES AI, and our partnership and founding of openfold and a sneak peak at early OpenFold3 results showing protein/ligand co-folding accuracy rivaling AF3

🚨 new paper alert 🚨 We present a method for designing protein nanoparticles with two unique faces that can bring together distinct biological targets at controlled distances! This project was led by Dr. Sanela Rankovic is out now in Nature Materials: tinyurl.com/yj8t476d

Excellent work, so much more to do in hybrid AI physics and data generation for protein/ligand, and openfold is working on both

Looking for a real world tutorial in using a suite of #ai #bioai tools to design antibodies with high developability using a chimeric design strategy? Terrific detailed walk-through from levitate.bio levitate.bio/antibody/tcr/c…

Happy to see our ipSAE score for AF3 models is useful for de novo binder design.

Exciting to see our protein binder design pipeline BindCraft published in its final form in nature ! This has been an amazing collaborative effort with Lennart, Christian Schellhaas, Sergey Ovchinnikov, Bruno Correia and many other amazing lab members and collaborators. nature.com/articles/s4158…