Reprogramming of arginine metabolism by supplementing a biopterin metabolite could convert cold breast tumors to hot tumors UToledo Medicine Case Comp Cancer Ctr hubs.la/Q02MRgT90

Take a look at this recently published paper in LSA: CC2D1A causes ciliopathy, intellectual disability, heterotaxy, renal dysplasia and abnormal CSF flow Yale School of Medicine Bursa Uludağ Üniversitesi hubs.la/Q02M985d0

Check out this reasearch article in LSA: Helminth protein enhances wound healing by inhibiting fibrosis and promoting tissue regeneration hubs.ly/Q02MlW8G0

A study by @Kirkland_Lab from OMRF shows that the cBAF complex efficiently opposes polycomb repressive complexes 1 and 2, a function not shared by gBAF or pBAF complexes life-science-alliance.org/content/7/11/e…

Identification of a new function for CSA protein in the regulation of the nuclear envelope, preventing nuclear ruptures and activation of inflammation pathways. Cambridge University Review Commons life-science-alliance.org/content/7/11/e…

The accumulation of mitochondrial double-stranded RNA (mt-dsRNA) in cancer cells depends on cell proliferation status. Tissue multiplex imaging reveals a build up of dsRNA in patient lung adenocarcinoma. Thomas MacVicar,CRUK Scotland Inst,UofG MVLS life-science-alliance.org/content/7/11/e…

Cryo-EM reveals that the R-domain of an ABC-C transporter encircles the ATP catalytic domain-1 in a tetra-phosphorylated manner and regulates the ATPase activity along with cellular transport. University of Arizona, University of Arizona Research, CBC @ UA, Rodolpho Carvalho, Shamiul Islam

The September issue includes articles showing that targeting Keap1 rescues C9orf72-related oxidative stress and motor deficits, cell–cell adhesion governs keratinocyte patterning, & much more! Link to issue: life-science-alliance.org/content/7/9

New article published in LSA: mTORC1 hampers Hedgehog signaling in Tsc2 deficient cells hubs.la/Q02MJhCd0

Check out this new article in LSA: Identification of single cell blasts in pediatric Acute Myeloid Leukemia using an Autoencoder The Becher Lab IBM Research Texas Children's hubs.la/Q02MRgVW0

Did you see this newly published article at LSA? Helicobacter pylori induces the expression of Lgr5 and stem cell properties in gastric target cells University of Zurich hubs.la/Q02MRl3j0

New article in LSA demonstrates how a shift of arginine metabolism from polyamine synthesis to nitric oxide synthesis induces reprogramming of macrophages from pro-tumor M2 to anti-tumor M1 types UToledo Medicine Case Comp Cancer Ctr hubs.la/Q02MR7f60

A Novel Role for CSA in Regulating Nuclear Envelope Integrity: Uncovering a Non-Canonical Function Cambridge University Review Commons hubs.la/Q02N8TVg0

New article published at LSA: Differential Modulation of Polycomb-Associated Histone Marks by cBAF, pBAF, and gBAF Complexes @Kirkland_Lab OMRF hubs.la/Q02N8yV80

Mitochondrial double-stranded RNA homeostasis depends on cell-cycle progression@tommacvicar,CRUK Scotland Inst,UofG MVLS hubs.la/Q02N8V870

Have you checked out the recently published paper by LSA? Cryo-EM reveals a phosphorylated R-domain envelops the NBD1 catalytic domain in an ABC transporter University of Arizona, University of Arizona Research, CBC @ UA, Rodolpho Carvalho, Shamiul Islam hubs.la/Q02N8z950

The article presents a cell interaction assay to study membrane protein interactions in quasi-physiological settings, with multiple applications, from deciphering interaction networks to assessing therapeutic molecules. Gustave Roussy CNRS 🌍 aymoz-bressot thibaud life-science-alliance.org/content/7/11/e…

Sleep disruption can accelerate neurodegeneration in Alzheimer's, while sleep induction helps clear toxic Tau proteins, improving neuronal function. UChicago Biological Sciences @UChicago_neuro Natalie Ortiz Vega life-science-alliance.org/content/7/11/e…

Mast cell extracellular traps catalyzed by peptidylarginine deiminase 4 contribute to vascular stasis and nerve injury which may contribute to acute and chronic pain in sickle cell disease. UC Irvine life-science-alliance.org/content/7/11/e…

Check out Kirkland lab's cool new study on recruiting different flavours of BAF using FIRE-Cas9!