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Latest from us: Analyses of over 4500 hospitalizations at Mount Sinai Health System suggests that individuals with #DownSyndrome are at higher risk of being hospitalized with #COVID19, and have worse outcomes. Led by amazing louisemalle. medrxiv.org/cgi/content/sh…

The first analysis of #COVID19 hospitalizations in people with #Downsyndrome found a higher-than-predicted rate of hospitalization at a younger age and with more severe outcomes at Mount Sinai Health System. 📈 bit.ly/308K6Kt medRxiv BogunovicLab #DSresearch #SARS_CoV_2

Latest from us. Individuals with #DownSyndrome admitted to the hospital with COVID19 have more severe disease. Led by louisemalle Lipschultz Precision Immunology Institute Icahn School of Medicine at Mount Sinai. Thank you Xiao-Fei Kong Columbia Medicine. Read more here: nature.com/articles/s4143…

Always nice to see an independent validation of what we recently published! Individuals with #DownSyndrome are at higher risk of severe #COVID19 acpjournals.org/doi/pdf/10.732… (read our findings here 👉nature.com/articles/s4143…) BogunovicLab

Thank you Dusan! And thank you to Mindich CHDI for inviting me to speak 🤩

Proud of Louise louisemalle. Her work on #DownSyndrome is featured in Science Magazine. SinaiMSTP Icahn School of Medicine at Mount Sinai Lipschultz Precision Immunology Institute Mindich CHDI sciencemag.org/news/2020/12/c…

Very nice to be interviewed in Science Magazine about our findings on #COVID19 in #DownSyndrome Important article raising awareness of an at-risk population Meredith Wadman BogunovicLab sciencemag.org/news/2020/12/c…

Check out our new paper where we describe a severe form of MIS-C in infants with Down syndrome. So glad to have been part of this collaborative effort 😀 Melissa Gans, MD @DrDouglasBush Casanova Lab Roosheel Patel BogunovicLab

Our review on Down syndrome and type I IFN highlights some really cool studies that seek to address the contribution of specific genes to this complex syndrome. So much more to be discovered…

Today! Excited (and a little nervous) to defend my PhD thesis, “Down syndrome: a paradox of immune suppression and autoimmunity.” Tune in :) 👉🏼 4/25 at 1-2pm EST, mssm.zoom.us/j/85362118034

Very excited that this is out! We show that sensitivity to IFN-I in Down syndrome results in increased negative regulation and susceptibility to viral infection. Thank you BogunovicLab and @Marta_MartinF. Read it in Immunity: authors.elsevier.com/c/1fv-43qNrUqG…

Why are individuals with #DownsSyndrome (DS) prone to #autoimmunity? @LouiseMalle1 in the BogunovicLab mapped the soluble and cellular immune landscape of individuals with DS to investigate. 🗺️ 📖 nature: go.nature.com/3Iz9D4e 🗨️: bit.ly/3mNeBCZ