#TeamMassSpec do you love mass spec so much it hurts? Me too :) Come work with us and get all the MS time your little heart desires. We are recruiting postdocs and staff scientists with proteomics experience to lead a variety of projects. kroganlab.ucsf.edu 1/4

Our Nature Microbiology asking what’s special about pandemic HIV Capsid is finally out. Thanks to Lorena Zuliani Alvarez, PhD for her green fingers, patience and general brilliance. Here’s some answers to the questions we get from eg @stuartjdneil

Thanks to everyone who came to #LoungeLigands last night QBI it was a great success @BShoichet thanks to Lorena Zuliani Alvarez, PhD and @poleary87 for the photos

I am looking to hire a Staff Research Associate UCLA QCBio UCLA Microbio, Immunology, & Molecular Genetics to serve as a lab manager and perform wet lab experiments related to mass spectrometry proteomics, virology, and molecular biology. If interested, please apply: hr.mycareer.ucla.edu/applicants/jsp…

Here is a nice tweetorial from Sophia Mädler with some more information on the computational aspects of our SPARCS approach. biorxiv.org/content/10.110… We are happy to share reagents and help establishing the protocol already pre-publication. Please RT.

Officially out in Cell: Systematic comparison of SARS-CoV-2 variants of concern (Alpha, Beta, Gamma, Delta, & Omicron) using global proteomic and genomic analyses during infection to understand the molecular responses driving viral evolution 🧵👇 cell.com/cell/fulltext/…

I'm so excited that our latest work addressing the role of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis is officially out today in Cell Host & Microbe !!! sciencedirect.com/science/articl…

CD8+ T cells in the cancer-immunity cycle: CD8+ T cells are “end effectors” of cancer immunity. Wherry, Kaech, Giles, & Globig review the current understanding of CD8+ T cell differentiation and function in cancer, discussing recent advances within a four-signal framework that

30+ years after caspases were found to be interleukin-1 converting enzymes (ICE), the first caspase-cytokine structure is revealed. We identify caspase-4 as a specific pro-IL-18 converting enzyme and describe the CryoEM structure of this enzyme-substrate interaction.

So excited to share our story revealing structures, functions and adaptations of the human LINE-1 retrotransposon, an ancient genetic parasite that has written 1/3 of the human genome and is implicated in cancer, aging, & autoimmunity. Now out in nature nature.com/articles/s4158…