Programmable bacteria as #cancer therapy: News & Views by Stephanie K. Dougan Dana-Farber covering recent work from Tal Danino and colleagues | go.nature.com/2GeccZP #ImmunoTherapy #SyntheticBiology

The process to develop and identify high performance FRET biosensors just got easier and more efficient, thanks to new work led by Longwei liu, a postdoc in UC San Diego Bioengineering professor yingxiao wang's lab. jacobsschoolofengineering.blogspot.com/2021/08/high-t… Nature Communications NIH-funded

Transient versus sustained #calcium increase upon single vs pulsed activation of #mechanosensor #Piezo1 can have opposite consequences or #FAK kinase activation Yingxiao Wang Longwei liu Michael Berns Shu Chien and collaborators UC San Diego UC San Diego Bioengineering embopress.org/doi/10.15252/e…

My recent review article entitled “Engineering chimeric antigen receptor T cells for solid tumour therapy” is online! Check it out: onlinelibrary.wiley.com/doi/10.1002/ct…

4 generations of bioengineers of Shu Chien lab got together @BMES_CMBE symposium Yingxiao Wang Ngan F Huang, PhD AijunWang,PhD

What better way to wrap up #cmbe2025 than with two outstanding talks by Longwei liu on getting T cells to "hear" for ultrasound-mediated CAR-T, and by @jbrunger on synthetic mechanoreceptors against neurodegenerarion (work by undergrad Dylan J.Conger!)

ICYMI by First Release - now officially in print Science Magazine Specific combinations of nutrients and metabolic enzymes determine T cell differentiation via loci-specific histone acetylations. buff.ly/4gvqKTz From Shixin Ma, Sue Kaech et al. #immunometabolism

Sonogenetic EchoBack-CAR T cells incorporate an ultrasensitive heat-shock promoter and synthetic positive feedback loop, enabling focused-ultrasound-controlled long-lasting CAR expression and enhanced anti-tumor efficacy. cell.com/cell/fulltext/… #NBThighlight

Now online! Engineering sonogenetic EchoBack-CAR T cells dlvr.it/TJzNbl

Happy to participate in this exciting project and now published in Nat. Biotech! 👏🏻👏🏻

How can we make immune cells hearing for therapy?