Six weeks left until the abstract deadline for Biology of Genomes at CSHL #BoG24! We have a stellar lineup of keynotes and discussion leaders (=~invited speakers), and look forward to another brilliant meeting in May 7-11. Abstract submission & info: meetings.cshl.edu/meetings.aspx?…

First author Richard Wolff and I are delighted to share our latest preprint on “Pervasive selective sweeps across human gut microbiomes” biorxiv.org/content/10.110… (1/n)

Just sharing that this exists 💙 mchb.hrsa.gov/national-mater…

#Geospatial Investigations in Colombia reveal variations in the distribution of mood and psychotic disorders by Song, Loes Olde Loohuis et al in Communications Medicine Inequitable geographic accessibility of specialty mental healthcare services. Targeting resources to identify severely ill

Our study on utilizing smartphones to track behavior in real-time & predict depression severity is now out in Nature Digital Medicine.  Jonathan Flint Sriram Sankararaman Eran Halperin UCLA Depression Grand Challenge

The UCLA Goodman-Luskin Endowed Postdoctoral Fellowship in Microbiome Research ($100K in salary + supplies) deadline is June 1. Get in touch if you would like to write a proposal together! And, get in touch even if your timeline is different - I am looking for a postdoc!

I've written the first part of a chapter on the heritability of IQ scores. Focusing on what IQ is attempting to measure. I highlight multiple paradoxical findings demonstrating IQ is not just "one innate thing". gusevlab.org/projects/hsq/#… I'll summarize the key points here. 🧵

[t.ly/vYqW7] Cancer biomarker discovery is historically mutation-centric, often neglecting the key role of genomics instability. Recently, we asked ourselves how do mutations and copy number alterations (CNAs) determine prognosis and tropism? 😋😋1/n

Today, RGC has published an important paper in nature today, describing an analysis of close to a million human exomes (n=983,578) as a single variant call set (!). This is the largest and most diverse rare variant database created so far. This impressive feat is accomplished by

Can we use genetics to predict which patients with depression will go on to develop bipolar disorder? Are depression and bipolar genetically different?🧬🧠

Panagiotaropoulou et al. recently performed a series of case-case GWAS to find out. Check out their recent pre-print: pubmed.ncbi.nlm.nih.gov/38410442/

We are thrilled to announce two open rank faculty searches U of Utah Human Genetics: a broad search for all areas of genetics research (utah.peopleadmin.com/postings/170913) & one focused on computational genomics faculty (utah.peopleadmin.com/postings/170449). This launches a multi-year recruiting initiative! (1/4)

🚨 Preprint 🚨 SSRI #antidepressant users report on whether drugs ‘helped’ them. In UK Biobank’s 2nd Mental Health Q, - 20k respondents reported on - 4 SSRI antidepressants, answering ‘yes’ or ‘no’ to whether specific drugs helped What do these reports capture? 1/7

1/n New preprint alert! 🚨🧬✨ The question we asked; is the genetic architecture of a complex trait different at the extreme ends of the distribution (i.e. tails) or similar to that in the main part of the trait distribution? #ASHG2024 #ASHG24 --> check out poster 4051T! 🧵👇🏾

Can’t wait to read this. Congrats Anil Ori, Paul O'Reilly and team!!