Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during mitotic exit biorxiv.org/cgi/content/sh… #biorxiv_cellbio

Excited to share our manuscript focusing on the impact of different aneuploidies on chromosomal instability! Jonne Raaijmakers Rene Medema Mar Soto RdelaT Michael Schubert and co-authors. biorxiv.org/content/10.110…

Even the longest, most excruciating experiments can be fun with the right colleagues to work with ❤️💚❤️💚

We are excited to share our new pre-print! We show that a previously-thought meiotic protein, MND1, has an important role enabling repair of two-ended DNA double-strand breaks in somatic cells. Great effort from everyone involved!

Super happy that our paper is out!! Ever wondered whether the chromatin environment determines DSB toxicity after CRISPR/Cas9? Great collaboration, including my amazing co-first author AnoekFriskes academic.oup.com/nar/advance-ar…

We identified dozens of DNA double-strand break repair proteins that modulate MMEJ:NHEJ balance depending on the local chromatin context: doi.org/10.1101/2022.1…

Have you ever wondered if your favourite DNA repair protein modulates pathway balance depending on the local chromatin context? Check out our latest pre-print from the Rene Medema and Bas van Steensel lab. A 🧵: biorxiv.org/content/10.110…

Delighted to share that our latest preprint is out! biorxiv.org/content/10.110… Something to read during the holidays! 🎄✨ Thanks to all contributors Jonne Raaijmakers Michael Schubert Mar Soto RdelaT Rene Medema