Each year, a brain affected by dementia shrinks up to four times faster than a healthy brain. That doesn’t sound ‘normal’ to us. Dementia is not a normal part of ageing, it’s caused by diseases. Help us build understanding. #ShareTheOrange.

Great new film from @MRC_LMB, Michel Goedert & Sjors Scheres on why they are working to decipher the structure of protein tau filaments in #dementia ⬇️

PhD student, Dani Pulgar Prieto, is studying proteasome localisation in neuronal and immune cells using super-resolution microscopy Imperial College London UK Dementia Research Institute #WomenInSTEM #WomenAtImperial #science #EqualityforAll #PhD #Postdoc #research #scientists #neurons #cells #glia

Post-doc Emma Mee Hayes, is studying proteasome localisation and function in iPSC-derived models of tau pathology Imperial College London UK Dementia Research Institute #WomenInSTEM #WomenAtImperial #science #EqualityforAll #PhD #Postdoc #research #scientists #neurons #cells #iPSC

Research technician, tomi, is using immunohistochemical techniques to optimise antibody-antigen platforms for use on biosensor devices that can detect biomarkers of neurodegenerative disease

Lab Manager, Megan Winterbotham, plays a vital role in the management and health and safety of the research laboratories within Imperial Department of Brain Sciences. UK Dementia Research Institute Imperial College London #WomenInSTEM #WomenAtImperial #EqualityforAll #research #scientists #science

Delighted to share our latest review paper - tinyurl.com/423eawdb! 🎉👩🏻‍🔬👩🏼‍🔬👨🏻‍🔬🎉 We propose that disaggregases and proteasomes act within transient aggregate-associated droplets (TAADs) to clear protein aggregates in neurodegenerative disorders!

We are recruiting Imperial Department of Brain Sciences a postdoc to study proteostasis and protein aggregation in neuronal models UK Dementia Research Institute using IPSC and 3D microscopy techniques, with possibility for extension. Please get in touch and help rt! tinyurl.com/522cm5ex

We are recruiting Imperial Department of Brain Sciences a postdoc to study proteasome activity on aggregates UK Dementia Research Institute using advanced imaging and biochemical techniques, with possibility for extension. Please get in touch and help rt! tinyurl.com/2p8k4mvy

Our latest paper is out now in PNASNews! Quantitative super-resolution microscopy of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies Fantastic effort from Mike Morten Liina Sirvio @yeyu_nj and collaborators! pnas.org/doi/10.1073/pn…

Researchers at the Crick, @UCL and MSD have identified a potential treatment target for a rare genetic type of childhood epilepsy. Read more about the study from Marisol Sampedro-Castaneda and Sila Ultanir 👇 crick.ac.uk/news-and-repor…

We have some exciting news to share from the Ye Lab! The first PhD student of the Ye Lab, Liina Sirvio, recently passed her PhD viva at Imperial College London! 🎉A big thanks to the excellent examiners Ed Tate and Catherine Lindon