OUT NOW 👉Enteric bacterial infection stimulates remodelling of bile metabolites to promote intestinal homeostasis nature.com/articles/s4156…

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. Djenet Bousbaine led the charge... nature 1/55

🎉 Happy New Year! To celebrate the holiday season, the Ting lab 中央研究院 Academia Sinica IMB Academia Sinica presents our latest discovery: Cpe1, a cysteine protease toxin bacteria use to outcompete their rivals. Preprint: biorxiv.org/content/10.110…

Today we report a compendium of human gut microbiomes with >168,000 samples We discovered distinct microbiome patterns across the globe, and show we can predict where a person lives just from their gut bacteria Now out in Cell cell.com/cell/fulltext/…

My lab’s first preprint! We used functional metagenomics to identify phage defenses in human and soil microbiomes. We scaled these selections while maintaining accuracy, enabling us to examine 9 habitats for defense elements against 7 phages. biorxiv.org/content/10.110… 1/10

🔬🦠 How to make sense of the taxonomic complexity & interpersonal variability of the gut microbiota? We propose that beneath this complexity lies a hierarchy of factors that control gut microbiota assembly. Read more! #Microbiome #GutHealth authors.elsevier.com/a/1km32_,2CiQu…

Out Now! An expanded metabolic pathway for androgen production by commensal bacteria bit.ly/42VVf0Y #Androgens #ProstateCancer #CancerResearch

Very excited to advertise the work of Charli in my lab! biorxiv.org/content/10.110…

Methylglyoxal: antibacterial effector Methylglyoxal produced by infected macrophages upon transition to aerobic glycolysis acts as an innate immune antimicrobial effector that bacteria must detoxify for virulence and to prevent mutations cell.com/cell-host-micr…

Congrats to postdoc Zhe Zhou on her paper out today in Cell Host & Microbe showing that gut bacteria cross-feed a common dietary antioxidant to produce energy under anaerobic conditions. Big thanks to collaborators Angela Jiang and Xiaofang Jiang NIH. sciencedirect.com/science/articl…